Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.63 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170598 | 0.91 | ADIPOR2 (0.67) | ADIPOR2ADIPOR1USP2MCHR1POLB | |
| SCHEMBL2211108 | 0.90 | UTS2R (0.62) | ADIPOR2ADIPOR1USP2MCHR1SIGMAR1 | |
| SCHEMBL17950944 | 0.90 | USP2 (0.77) | ADIPOR2ADIPOR1USP2MCHR1POLB | |
| SCHEMBL17950923 | 0.90 | ADIPOR2 (0.63) | ADIPOR2ADIPOR1USP2MCHR1POLB | |
| SCHEMBL17950986 | 0.90 | POLB (0.63) | ADIPOR2ADIPOR1USP2MCHR1POLB | |
| SCHEMBL17950896 | 0.90 | POLB (0.63) | ADIPOR2ADIPOR1USP2MCHR1POLB | |
| SCHEMBL17951031 | 0.90 | MCHR1 (0.68) | ADIPOR2ADIPOR1USP2MCHR1POLB | |
| SCHEMBL4036078 | 0.90 | POLB (0.65) | ADIPOR2ADIPOR1USP2MCHR1POLB | |
| SCHEMBL2213070 | 0.90 | UTS2R (0.64) | ADIPOR2ADIPOR1USP2MCHR1SIGMAR1 | |
| SCHEMBL24514569 | 0.89 | ADIPOR2 (0.70) | ADIPOR2ADIPOR1USP2MCHR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160214967-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | THE UNIVERSITY OF TOKYO (JP) | 2016-07-28 | — | — | US | disclosed |
| EP-1389616-B1 | 3,4-Dihalobenzylpiperidine derivatives and their medical use | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-07-27 | — | — | EP | disclosed |
| US-7115635-B2 | Benzylpiperidine compound | MITSUBISHI PHARMA CORPORATION (JP) | 2006-10-03 | — | — | US | disclosed |
| US-20040158071-A1 | Chemokine inhibitors and stability in blood | MITSUBISHI PHARMA CORPORATION (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1389616-A1 | NOVEL BENZYLPIPERIDINE COMPOUND | Mitsubishi Pharma Corporation (JP) | 2004-02-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214967-A1 | ACTIVATOR OF ADIPONECTIN RECEPTOR | ADIPOR1, ADIPOR2, CCKAR | ADIPOR2 2/4885ADIPOR1 1/4885USP2 3101/4885 |
| US-20040158071-A1 | Chemokine inhibitors and stability in blood | CCL2, CXCR1, CCR5 | ADIPOR2 1344/4885ADIPOR1 782/4885USP2 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.