Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 4/20 | 0.35 |
| ▸ | IRS1 | P35568 | 3/20 | 0.35 |
| ▸ | GAB1 | Q13480 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22105971 | 0.96 | TDP1 (0.38) | GHSRTDP1AKT1IRS1GAB1 | |
| SCHEMBL22105998 | 0.89 | NAMPT (0.38) | TDP1NAMPT | |
| SCHEMBL22105999 | 0.88 | TDP1 (0.39) | GHSRTDP1KDM4ELMNA | |
| SCHEMBL22105963 | 0.86 | HDAC3 (0.41) | KDM4ELMNAHDAC1 | |
| SCHEMBL22111934 | 0.84 | ALDH1A1 (0.35) | TDP1 | |
| SCHEMBL22105974 | 0.82 | TDP1 (0.37) | TDP1NAMPTHDAC1CASP6 | |
| SCHEMBL31682097 | 0.82 | TBXA2R (0.43) | GHSRTDP1AKT1IRS1GAB1 | |
| SCHEMBL31681966 | 0.82 | TBXA2R (0.43) | GHSRTDP1AKT1IRS1GAB1 | |
| SCHEMBL31682020 | 0.82 | TBXA2R (0.43) | GHSRTDP1AKT1IRS1GAB1 | |
| SCHEMBL22105937 | 0.80 | HDAC3 (0.41) | KDM4ENAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120463-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-18 | — | — | WO | disclosed |