Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.33 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.33 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.33 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029350 | 0.87 | TDP1 (0.41) | TDP1CCR9CASP6MEN1KMT2A | |
| SCHEMBL22105971 | 0.87 | TDP1 (0.38) | TDP1CASP6PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL22105945 | 0.85 | ALDH1A1 (0.33) | TDP1MEN1KMT2APLAAT3PLAAT5 | |
| SCHEMBL24257938 | 0.83 | TDP1 (0.44) | TDP1CCR9MEN1KMT2A | |
| SCHEMBL22106155 | 0.82 | GHSR (0.38) | TDP1CASP6HDAC1NAMPT | |
| SCHEMBL22029368 | 0.82 | TDP1 (0.45) | TDP1CCR9MEN1KMT2APTPN1 | |
| SCHEMBL22105963 | 0.80 | HDAC3 (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL22111934 | 0.77 | ALDH1A1 (0.35) | TDP1ALDH1A1CACNA1B | |
| SCHEMBL22106005 | 0.74 | CA2 (0.44) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL22105998 | 0.73 | NAMPT (0.38) | TDP1MEN1KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120463-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2020-06-18 | — | — | WO | disclosed |