Terephthalamide

Terephthalamide

SCHEMBL221067

NC(=O)c1ccc(C(N)=O)cc1.Nc1ccccc1N

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.67
PARP1 P09874 2/20 0.67
MAPT P10636 2/20 0.67
TSHR P16473 2/20 0.67
POLB P06746 1/20 0.67
CYP2C19 P33261 1/20 0.67
RECQL P46063 1/20 0.67
BLM P54132 1/20 0.67
PMP22 Q01453 1/20 0.67
HSD17B10 Q99714 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
PARP10 Q53GL7 8/20 0.56
PLA2G10 O15496 1/20 0.56
PLA2G2A P14555 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.53
ALOX15 P16050 1/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
PARP4 Q9UKK3 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28759686 0.93 PARP10 (0.61) CYP3A4PARP1MAPTTSHRPOLB
Benzamide SCHEMBL4016379 0.92 PARP1 (0.80) CYP3A4PARP1MAPTTSHRPOLB
SCHEMBL9352356 0.87 PARP1 (0.56) CYP3A4PARP1MAPTTSHRPOLB
Terephthalamide SCHEMBL27486747 0.83 PARP1 (0.94) CYP3A4PARP1MAPTTSHRPOLB
SCHEMBL3338240 0.83 PARP1 (0.59) CYP3A4PARP1MAPTTSHRPOLB
Terephthalamide SCHEMBL27828697 0.83 PARP1 (0.82) CYP3A4PARP1MAPTTSHRPOLB
Terephthalamide SCHEMBL23774 0.83 PARP1 (0.71) CYP3A4PARP1MAPTTSHRPOLB
SCHEMBL3790628 0.83 MKNK1 (0.59) CYP3A4PARP1MAPTTSHRPOLB
Terephthalamide SCHEMBL28128192 0.82 TSHR (0.71) CYP3A4PARP1MAPTTSHRPOLB
Terephthalamide SCHEMBL7564599 0.81 PARP1 (0.70) CYP3A4PARP1MAPTTSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3918174-A1 HOT MELT SINGLE-COMPONENT PRIMARY SEALANT Bostik SA (FR) 2021-12-08 EP claimed
WO-2020157071-A1 HOT MELT SINGLE-COMPONENT PRIMARY SEALANT BOSTIK SA (FR) 2020-08-06 WO claimed
EP-3690175-A1 HOT MELT SINGLE-COMPONENT PRIMARY SEALANT Bostik SA (FR) 2020-08-05 EP claimed
CN-110446805-A Fabric and the work clothes being produced from it TEIJIN ARAMID GMBH 2019-11-12 CN claimed
CN-109950615-A A kind of preparation method of composition polymer solid electrolyte 华北电力大学 2019-06-28 CN claimed
CN-107128038-B Fabric composite for thermal protection article 杜邦公司 2019-06-18 CN claimed
CN-109891023-A Fabric with the cut resistant coating comprising para-aramid particle 纳幕尔杜邦公司 2019-06-14 CN claimed
CN-208903709-U A kind of Multi-core branch combined cable 福建中裕电缆有限公司 2019-05-24 CN claimed
CN-109705529-A A kind of preparation method based on Fanglun l414 fibrous composite 蓝星(成都)新材料有限公司 2019-05-03 CN claimed
CN-109689956-A The carbon containing aromatic poly-amide fabric of resistance to electric arc from different yarns 纳幕尔杜邦公司 2019-04-26 CN claimed
CN-1234839-A Process for making high tenacity aramid fibers DU PONT (US) 1999-11-10 CN claimed
US-5977241-A Polymer and inorganic-organic hybrid composites and methods for making same INTEGUMENT TECHNOLOGIES, INC. (US) 1999-11-02 US claimed
WO-1998037964-A9 POLYMER COMPOSITES AND METHODS FOR MAKING AND USING SAME 1999-01-21 WO claimed
WO-1998037964-A1 POLYMER COMPOSITES AND METHODS FOR MAKING AND USING SAME INTEGUMENT TECHNOLOGIES, INC. (US) 1998-09-03 WO claimed
CN-1172510-A Process for batch-plating aramid fibers DU PONT (US) 1998-02-04 CN claimed
CN-1032323-C Process for preparing strong aromater Polyamide papers of high porosity DU PONT (US) 1996-07-17 CN claimed
CN-1083883-A The method of the powerful aramid paper of preparation high-air-permeability DU PONT (US) 1994-03-16 CN claimed
CN-1082634-A Low polymerization degree is right-the polyarylamide spinning solution SUMITOMO CHEMICAL CO (JP) 1994-02-23 CN claimed
CN-1072226-A BALLISTIC COMPOSITE DU PONT (US) 1993-05-19 CN claimed
CN-1048710-A The preparation method of high viscosity PPTA CHENGDU TECHNICAL SERVICE CENT (CN) 1991-01-23 CN claimed