Terephthalamide

Terephthalamide

SCHEMBL27828697

NC(=O)c1ccc(C(N)=O)cc1.c1ccccc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.82
TSHR P16473 2/20 0.82
POLB P06746 1/20 0.82
CYP3A4 P08684 1/20 0.82
MAPT P10636 1/20 0.82
CYP2C19 P33261 1/20 0.82
RECQL P46063 1/20 0.82
BLM P54132 1/20 0.82
PMP22 Q01453 1/20 0.82
HSD17B10 Q99714 1/20 0.82
TDP1 Q9NUW8 1/20 0.82
L3MBTL1 Q9Y468 1/20 0.82
PARP10 Q53GL7 10/20 0.65
PLA2G10 O15496 1/20 0.65
PLA2G2A P14555 1/20 0.65
PARP15 Q460N3 2/20 0.62
PARP4 Q9UKK3 2/20 0.62
ALDH1A1 P00352 1/20 0.62
KMT2A Q03164 1/20 0.62
PARP14 Q460N5 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL27486747 0.94 PARP1 (0.94) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL23774 0.93 PARP1 (0.71) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamic Acid SCHEMBL6859681 0.91 PARP10 (0.71) PARP1TSHRPOLBCYP3A4MAPT
Benzamide SCHEMBL29618402 0.90
Benzamide SCHEMBL1332331 0.90
Benzamide SCHEMBL30112947 0.90 PARP1 (1.00) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL31486652 0.90 TSHR (0.68) PARP1TSHRPOLBCYP3A4MAPT
SCHEMBL21755166 0.90 PARP1 (1.00) PARP1TSHRPOLBCYP3A4MAPT
Benzamide SCHEMBL16352 0.90
Benzamide SCHEMBL1222101 0.90 PARP1 (1.00) PARP1TSHRPOLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110423453-A A kind of high-intensity anti-cracking cable sheath material and preparation method thereof ANHUI SHANGHUA CABLE CO LTD 2019-11-08 CN claimed
CN-218004439-U High-strength reel cable 天津瑞源电缆有限公司 2022-12-09 CN disclosed
CN-110588123-A Wear-resistant non-woven fabric 江苏金荣泰新材料科技有限公司 2019-12-20 CN disclosed
CN-106458962-A NOVEL COMPLEXES FOR THE SEPARATION OF CATIONS 巴黎第十大学 2017-02-22 CN disclosed
CN-103081190-B Positive active material SUMITOMO CHEMICAL CO.,LTD. (JP) 2016-01-20 CN disclosed
CN-103081190-A Positive electrode active material SUMITOMO CHEMICAL CO 2013-05-01 CN disclosed
CN-101993534-A Method for preparing aromatic polyamide polymer and method for preparing aramid fiber by using same KOLON INC 2011-03-30 CN disclosed