SCHEMBL22107

SCHEMBL22107

CC(C)(C)c1c(OOC(N)=O)cccc1[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
HTT P42858 1/20 0.45
TDP1 Q9NUW8 4/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
TSHR P16473 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
GAA P10253 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
KMT2A Q03164 1/20 0.39
KDM4E B2RXH2 1/20 0.38
GPR35 Q9HC97 1/20 0.38
MAPT P10636 1/20 0.37
F2 P00734 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7647974 0.82 TDP1 (0.41) ALDH1A1HTTTDP1L3MBTL1TSHR
SCHEMBL12988187 0.81 ALDH1A1 (0.53) ALDH1A1HTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL30880318 0.81 ALDH1A1 (0.53) ALDH1A1HTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL22108 0.78 TDP1 (0.39) ALDH1A1HTTTDP1L3MBTL1TSHR
SCHEMBL28313485 0.77 ALDH1A1 (0.62) ALDH1A1HTTTDP1L3MBTL1TSHR
SCHEMBL18286925 0.75 TDP1 (0.58) ALDH1A1HTTTDP1L3MBTL1TSHR
SCHEMBL2302322 0.74 KMT2A (0.44) ALDH1A1HTTTDP1L3MBTL1TSHR
SCHEMBL28461286 0.73 BCL9 (0.48) ALDH1A1HTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL23421580 0.72 TDP1 (0.56) ALDH1A1HTTTDP1L3MBTL1TSHR
SCHEMBL27792482 0.71 ALDH1A1 (0.54) ALDH1A1HTTTDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
US-10105908-B2 Process for producing modified olefin polymer in an extruder BOREALIS AG (AT) 2018-10-23 US claimed
US-20170361543-A1 Process for Producing Modified Olefin Polymer in an Extruder BOREALIS AG (AT) 2017-12-21 US claimed
WO-2016124617-A1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2016-08-11 WO claimed
US-12605917-B2 Multilayer sheet comprising a foamed layer suitable for food packaging BOREALIS AG (AT) 2026-04-21 US disclosed
US-20240247140-A1 FLAME RETARDANT COMPOSITION COMPRISING A HIGH MELT STRENGTH POLYPROPYLENE BOREALIS AG (AT) 2024-07-25 US disclosed
WO-2024141547-A1 PROPYLENE COMPOSITION BOREALIS AG (AT) 2024-07-04 WO disclosed
EP-4393969-A1 PROPYLENE COMPOSITION Borealis AG (AT) 2024-07-03 EP disclosed
EP-3487927-B1 STIFF PROPYLENE COMPOSITION WITH GOOD DIMENSIONAL STABILITY AND EXCELLENT SURFACE APPEARANCE BOREALIS AG (AT) 2024-03-27 EP disclosed
EP-3532540-B1 HIGH FLOW HETEROPHASIC POLYPROPYLENE COPOLYMERS WITH IMPROVED MECHANICAL AND OPTICAL PROPERTIES BOREALIS AG (AT) 2024-03-13 EP disclosed
US-20230405969-A1 MULTILAYER SHEET COMPRISING A FOAMED LAYER SUITABLE FOR FOOD PACKAGING BOREALIS AG (AT) 2023-12-21 US disclosed
US-20230227620-A1 HMS PP FOAM SHEET WITH GOOD COMPRESSIVE STRENGTH AND RECOVERABILITY BOREALIS AG (AT) 2023-07-20 US disclosed
US-20010016628-A1 Modified with less than 5% by weight of monofunctional, difunctional and polyfunctional monomers; improved melt processability; sheets, films, panels, coatings, pipes, hollow objects and foams BOREALIS GMBH (AU) 2001-08-23 US disclosed
US-6242525-B1 PROPYLENE HOMOPOLYMERS AND/OR COPOLYMERS WITH ELASTOMERS OF READILY VOLATILE DIENES IN THE PRESENCE OF THERMALLY DECOMPOSING FREE RADICAL-FORMING AGENTS; THERMOPLASTIC ELASTOMERS WITH A FINE DISPERSION DISTRIBUTION BOREALIS GMBH (AT) 2001-06-05 US disclosed
US-6225366-B1 USED IN PACKAGING SECTOR, MOTOR VEHICLE PARTS, SPORTS AND LEISURE EQUIPMENT, INDUSTRIAL APPLICATIONS, AS WELL AS APPLICATIONS IN THE BUILDING MATERIAL BOREALIS AG (AT) 2001-05-01 US disclosed
US-6218011-B1 Polyolefin fibers and polyolefin yarns and textile fabrics produced therefrom BOREALIS GMBH (AT) 2001-04-17 US disclosed
US-6204348-B1 REACTING A POLYPROPYLENE WITH ETHYLENICALLY UNSATURATED MONOMER BOREALIS GMBH (AT) 2001-03-20 US disclosed
US-6136926-A CURING WITH ETHYLENICALLY UNSATURATED ORGANOSILANE COMPOUND; HEATING BELOW SOFTENING POINT BOREALIS GMBH (AT) 2000-10-24 US disclosed
US-5962594-A Segmented polyolefins BOREALIS AG (AT) 1999-10-05 US disclosed
US-5929127-A Fine-celled polyolefin foam materials BOREALIS AG (AT) 1999-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605917-B2 Multilayer sheet comprising a foamed layer suitable for food packaging PTGER3, MFAP1, TAS2R13 ALDH1A1 4516/4885HTT 2815/4885TDP1 4361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.