Sugi Predict

Sugi Predict / Compounds / SCHEMBL22108

SCHEMBL22108

SCHEMBL22108

CC(C)(C)c1cccc(OOC(N)=O)c1[N+](=O)[O-]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 0.39
▸ L3MBTL1 Q9Y468 3/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ POLB P06746 1/20 0.39
▸ CTDSP1 Q9GZU7 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.37
▸ ALDH1A1 P00352 6/20 0.36
▸ HTT P42858 2/20 0.36
▸ TSHR P16473 3/20 0.34
▸ ATM Q13315 2/20 0.34
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.33
▸ GALR3 O60755 1/20 0.33
▸ GABRA1 P14867 1/20 0.33
▸ GABRB2 P47870 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ TP53 P04637 1/20 0.32
▸ GAA P10253 1/20 0.32
▸ RXRA P19793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22107 0.78 ALDH1A1 (0.45) TDP1L3MBTL1KDM4ENPSR1ALDH1A1
SCHEMBL31189367 0.77 ALDH1A1 (0.36) TDP1L3MBTL1NPSR1ALDH1A1HTT
SCHEMBL7647974 0.77 TDP1 (0.41) TDP1L3MBTL1KDM4EPOLBCTDSP1
SCHEMBL4600270 0.75 NPSR1 (0.37) TDP1L3MBTL1KDM4EPOLBCTDSP1
SCHEMBL7857028 0.75 TDP1 (0.41) TDP1L3MBTL1KDM4EPOLBCTDSP1
SCHEMBL2302324 0.74 PPARA (0.40) TDP1L3MBTL1KDM4EPOLBCTDSP1
SCHEMBL12988187 0.71 ALDH1A1 (0.53) TDP1L3MBTL1KDM4EPOLBALDH1A1
SCHEMBL30880318 0.71 ALDH1A1 (0.53) TDP1L3MBTL1KDM4EPOLBALDH1A1
SCHEMBL6003012 0.71 TDP1 (0.36) TDP1L3MBTL1KDM4EPOLBCTDSP1
SCHEMBL2080615 0.69 RAB9A (0.40) NPSR1ALDH1A1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 — — EP claimed
US-10105908-B2 Process for producing modified olefin polymer in an extruder BOREALIS AG (AT) 2018-10-23 — — US claimed
US-20170361543-A1 Process for Producing Modified Olefin Polymer in an Extruder BOREALIS AG (AT) 2017-12-21 — — US claimed
WO-2016124617-A1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2016-08-11 — — WO claimed
US-12605917-B2 Multilayer sheet comprising a foamed layer suitable for food packaging BOREALIS AG (AT) 2026-04-21 — — US disclosed
US-20240247140-A1 FLAME RETARDANT COMPOSITION COMPRISING A HIGH MELT STRENGTH POLYPROPYLENE BOREALIS AG (AT) 2024-07-25 — — US disclosed
WO-2024141547-A1 PROPYLENE COMPOSITION BOREALIS AG (AT) 2024-07-04 — — WO disclosed
EP-4393969-A1 PROPYLENE COMPOSITION Borealis AG (AT) 2024-07-03 — — EP disclosed
EP-3487927-B1 STIFF PROPYLENE COMPOSITION WITH GOOD DIMENSIONAL STABILITY AND EXCELLENT SURFACE APPEARANCE BOREALIS AG (AT) 2024-03-27 — — EP disclosed
EP-3532540-B1 HIGH FLOW HETEROPHASIC POLYPROPYLENE COPOLYMERS WITH IMPROVED MECHANICAL AND OPTICAL PROPERTIES BOREALIS AG (AT) 2024-03-13 — — EP disclosed
US-20230405969-A1 MULTILAYER SHEET COMPRISING A FOAMED LAYER SUITABLE FOR FOOD PACKAGING BOREALIS AG (AT) 2023-12-21 — — US disclosed
US-20230227620-A1 HMS PP FOAM SHEET WITH GOOD COMPRESSIVE STRENGTH AND RECOVERABILITY BOREALIS AG (AT) 2023-07-20 — — US disclosed
US-20010016628-A1 Modified with less than 5% by weight of monofunctional, difunctional and polyfunctional monomers; improved melt processability; sheets, films, panels, coatings, pipes, hollow objects and foams BOREALIS GMBH (AU) 2001-08-23 — — US disclosed
US-6242525-B1 PROPYLENE HOMOPOLYMERS AND/OR COPOLYMERS WITH ELASTOMERS OF READILY VOLATILE DIENES IN THE PRESENCE OF THERMALLY DECOMPOSING FREE RADICAL-FORMING AGENTS; THERMOPLASTIC ELASTOMERS WITH A FINE DISPERSION DISTRIBUTION BOREALIS GMBH (AT) 2001-06-05 — — US disclosed
US-6225366-B1 USED IN PACKAGING SECTOR, MOTOR VEHICLE PARTS, SPORTS AND LEISURE EQUIPMENT, INDUSTRIAL APPLICATIONS, AS WELL AS APPLICATIONS IN THE BUILDING MATERIAL BOREALIS AG (AT) 2001-05-01 — — US disclosed
US-6218011-B1 Polyolefin fibers and polyolefin yarns and textile fabrics produced therefrom BOREALIS GMBH (AT) 2001-04-17 — — US disclosed
US-6204348-B1 REACTING A POLYPROPYLENE WITH ETHYLENICALLY UNSATURATED MONOMER BOREALIS GMBH (AT) 2001-03-20 — — US disclosed
US-6136926-A CURING WITH ETHYLENICALLY UNSATURATED ORGANOSILANE COMPOUND; HEATING BELOW SOFTENING POINT BOREALIS GMBH (AT) 2000-10-24 — — US disclosed
US-5962594-A Segmented polyolefins BOREALIS AG (AT) 1999-10-05 — — US disclosed
US-5929127-A Fine-celled polyolefin foam materials BOREALIS AG (AT) 1999-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605917-B2 Multilayer sheet comprising a foamed layer suitable for food packaging PTGER3, MFAP1, TAS2R13 TDP1 4361/4885L3MBTL1 3208/4885KDM4E 4325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.