Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30948864 | 0.88 | MET (0.71) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL30948872 | 0.88 | MET (0.71) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22109410 | 0.88 | MET (0.71) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22109202 | 0.86 | MET (0.51) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL30948857 | 0.86 | MET (0.51) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22109327 | 0.80 | MET (0.67) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2571903 | 0.78 | MET (1.00) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22109348 | 0.76 | MET (0.69) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22109163 | 0.76 | MET (0.56) | MET | |
| SCHEMBL30948858 | 0.76 | MET (0.56) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2020124060-A1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA, INC. (US) | 2020-06-18 | — | — | WO | disclosed |