SCHEMBL30948858

SCHEMBL30948858

Cn1cc2cc(Cn3nnc4ncc(-c5ccc(P(C)(C)=O)c(F)c5)nc43)c(F)cc2n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MET P08581 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22109163 1.00 MET (0.56) MET
SCHEMBL22109382 0.92 MET (0.53) MET
SCHEMBL22109306 0.90 MET (0.58) MET
SCHEMBL30948880 0.90 MET (0.58) MET
SCHEMBL30948857 0.88 MET (0.51) MET
SCHEMBL22109202 0.88 MET (0.51) MET
SCHEMBL22109155 0.87 MET (0.56) MET
SCHEMBL22109154 0.84 MET (0.55) MET
SCHEMBL30948866 0.83 MET (0.59) MET
SCHEMBL22109381 0.82 MET (0.53) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12258365-B2 Organophosphorus-substituted compounds as c-MET inhibitors and therapeutic uses thereof BETA PHARMA, INC. (US) 2025-03-25 US disclosed
EP-3893872-B1 ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF BETA PHARMA INC (US) 2024-07-17 EP disclosed
CN-113412112-B Organophosphorus substituted compounds as c-MET inhibitors and therapeutic uses thereof 贝达医药公司 2024-06-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12258365-B2 Organophosphorus-substituted compounds as c-MET inhibitors and therapeutic uses thereof MET, ALK, TYRO3 MET 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.