Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19018503 | 1.00 | TSHR (0.36) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL19018553 | 1.00 | TSHR (0.36) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL22109441 | 0.80 | TSHR (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL31189826 | 0.75 | TSHR (0.43) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL13294314 | 0.74 | TSHR (0.54) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL19018802 | 0.73 | — | — | |
| SCHEMBL22109082 | 0.73 | — | — | |
| SCHEMBL19018754 | 0.73 | — | — | |
| SCHEMBL19018521 | 0.73 | — | — | |
| SCHEMBL19018543 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200188540-A1 | CONFORMATIONALLY STRAINED TRANS-CYCLOALKENES FOR RADIOLABELING | UNIVERSITY OF DELAWARE (US) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200188540-A1 | CONFORMATIONALLY STRAINED TRANS-CYCLOALKENES FOR RADIOLABELING | CYCS, PCNA, CTSS | TSHR 316/4885SMN1; SMN2 4408/4885ALDH1A1 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.