Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109368 | 0.92 | MET (0.58) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22109395 | 0.89 | MET (0.67) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL30948878 | 0.89 | MET (0.67) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22109329 | 0.83 | MET (0.59) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL30948868 | 0.82 | MET (0.75) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL22109390 | 0.82 | MET (0.75) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2575316 | 0.81 | MET (0.72) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL29314630 | 0.80 | MET (0.71) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL28922896 | 0.80 | MET (0.70) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL2571074 | 0.79 | MET (0.65) | METCYP2C9PDE3BPDE3APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2020124060-A1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA, INC. (US) | 2020-06-18 | — | — | WO | disclosed |