Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212544 | 1.00 | TRPA1 (0.56) | TRPA1CYP1A2EPHX1TSHRTRPV1 | |
| SCHEMBL25158 | 1.00 | TRPA1 (0.56) | TRPA1CYP1A2EPHX1TSHRTRPV1 | |
| Hydrochloric Acid SCHEMBL28131666 | 0.98 | TRPA1 (0.54) | TRPA1CYP1A2EPHX1TSHRTRPV1 | |
| Dimethylamine SCHEMBL28101946 | 0.91 | TRPA1 (0.53) | TRPA1TRPV1SLC6A2TAAR1MAOA | |
| SCHEMBL8752288 | 0.89 | TRPA1 (0.50) | TRPA1CYP1A2EPHX1TSHRTRPV1 | |
| SCHEMBL1833635 | 0.87 | TRPA1 (0.55) | TRPA1CYP1A2EPHX1TSHRTRPV1 | |
| Di(Hydroxyethyl)Ether SCHEMBL28301309 | 0.86 | TRPA1 (0.45) | TRPA1CYP1A2EPHX1TSHRTRPV1 | |
| Acrylic Acid SCHEMBL29037084 | 0.84 | TRPA1 (0.51) | TRPA1CYP1A2TRPV1SRRALPI | |
| Ammonia Solution, Strong SCHEMBL29021310 | 0.84 | TRPA1 (0.53) | TRPA1CYP1A2EPHX1TSHRTRPV1 | |
| SCHEMBL10777895 | 0.83 | TRPA1 (0.50) | TRPA1TSHRPKMSLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589446-B1 | N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors | BOEHRINGER INGELHEIM CA LTD (CA) | 1997-09-03 | — | — | EP | claimed |
| EP-0317998-B1 | Manufacturing method of optically-active 1,2-diols | KANEGAFUCHI CHEMICAL IND (JP) | 1994-08-31 | — | — | EP | claimed |
| US-4981796-A | BIOSYNTHESIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-01 | — | — | US | claimed |
| EP-0317998-A2 | Manufacturing method of optically-active 1,2-diols | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-05-31 | — | — | EP | claimed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200278346-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ADJACENT ACQUISITION CO., LLC | 2020-09-03 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| US-20150309021-A1 | Advanced Drug Development and Manufacturing | LOS ALAMOS NATIONAL SECURITY, LLC | 2015-10-29 | — | — | US | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |
| EP-1175382-B1 | METHOD FOR THE DIHYDROXYLATION OF OLEFINS USING TRANSITION-METAL CATALYSTS | BAYER CHEMICALS AG (DE) | 2005-02-09 | — | — | EP | disclosed |
| EP-0317998-B1 | Manufacturing method of optically-active 1,2-diols | KANEGAFUCHI CHEMICAL IND (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-4981796-A | BIOSYNTHESIS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-01 | — | — | US | disclosed |
| EP-0317998-A2 | Manufacturing method of optically-active 1,2-diols | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-05-31 | — | — | EP | disclosed |
| EP-0031877-B1 | OPTICALLY ACTIVE 1,2-BIS-(DIPHENYLPHOSPHINO)-COMPOUNDS, METAL COMPLEXES CONTAINING THEM AS CHIRAL LIGANDS AND THEIR USE | Degussa Aktiengesellschaft (DE) | 1983-02-02 | — | — | EP | disclosed |
| US-4356324-A | CHIRAL LIGANDS FOR RHODIUM HYDROGENATION CATALYSTS | DEGUSSA AKTIENGESELLSCHAFT, A GERMAN CORP. (DE) | 1982-10-26 | — | — | US | disclosed |
| EP-0031877-A1 | Optically active 1,2-Bis-(diphenylphosphino)-compounds, metal complexes containing them as chiral ligands and their use | Degussa Aktiengesellschaft (DE) | 1981-07-15 | — | — | EP | disclosed |