SCHEMBL1833635

SCHEMBL1833635

OC(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.55
TSHR P16473 1/20 0.55
EPHX1 P07099 1/20 0.55
CYP1A2 P05177 1/20 0.54
SLC6A2 P23975 2/20 0.50
TAAR1 Q96RJ0 2/20 0.50
SRR Q9GZT4 2/20 0.50
MAOA P21397 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
CYP2A6 P11509 1/20 0.50
ADORA2A P29274 1/20 0.50
ADORA1 P30542 1/20 0.50
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
PTGS1 P23219 1/20 0.50
XIAP P98170 1/20 0.50
SLC7A5 Q01650 1/20 0.50
ALPL P05186 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29021310 0.97 TRPA1 (0.53) TRPA1TSHREPHX1CYP1A2SLC6A2
SCHEMBL3091848 0.89 TRPA1 (0.52) TRPA1EPHX1CYP1A2SLC6A2TAAR1
SCHEMBL3091836 0.89 TRPA1 (0.52) TRPA1EPHX1CYP1A2SLC6A2TAAR1
SCHEMBL5105980 0.89 TRPA1 (0.52) TRPA1EPHX1CYP1A2SLC6A2TAAR1
Hypophosphorous Acid SCHEMBL3367718 0.88 TRPA1 (0.52) TRPA1TSHREPHX1CYP1A2SRR
SCHEMBL2211027 0.87 TRPA1 (0.56) TRPA1TSHREPHX1CYP1A2SLC6A2
SCHEMBL25158 0.87 TRPA1 (0.56) TRPA1TSHREPHX1CYP1A2SLC6A2
SCHEMBL2212544 0.87 TRPA1 (0.56) TRPA1TSHREPHX1CYP1A2SLC6A2
SCHEMBL8202062 0.86 TRPA1 (0.46) TRPA1TSHREPHX1CYP1A2SLC6A2
SCHEMBL5982885 0.86 SLC18A3 (0.53) TRPA1EPHX1CYP1A2SIGMAR1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103242371-A Aryl-pyridine cyclic Pd-N heterocyclic carbene compound as well as preparation method and application thereof UNIV LUOYANG NORMAL 2013-08-14 CN claimed
US-20090012044-A1 Novel Hiv Protease Inhibitors VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE (CZ) 2009-01-08 US claimed
EP-1732570-A2 NOVEL HIV PROTEASE INHIBITORS Vysoká skola chemicko-technologická v Praze (CZ) 2006-12-20 EP claimed
WO-2005073240-A2 NOVEL HIV PROTEASE INHIBITORS Vysoká skola chemicko-technologická v Praze (CZ) 2005-08-11 WO claimed
US-6812354-B2 MILD CATALYTIC REDUCTION OF 3-HYDROXYMETHYLTETRAHYDROFURAN OR 3-FORMYLTETRAHYDROFURAN WITH SECONDARY ALCOHOL HYDROGEN SOURCE EASTMAN KODAK COMPANY 2004-11-02 US claimed
US-20040122241-A1 Process for preparing 3-methyltetrahydrofuran EASTMAN CHEMICAL COMPANY 2004-06-24 US claimed
EP-1431295-A1 Process for the preparation of 3-methyltetrahydrofuran EASTMAN CHEMICAL COMPANY (US) 2004-06-23 EP claimed
EP-3191437-B1 PROCESS FOR HYDROXYLATING PHENOLIC SUBSTRATE SPECIALTY OPERATIONS FRANCE (FR) 2025-10-01 EP disclosed
CN-112789108-B Catalyst for asymmetric hydrogenation of compounds containing carbon double bonds 格拉斯如睦株式会社 2023-09-19 CN disclosed
CN-107108417-B Process for hydroxylating phenolic substrates 罗地亚经营管理公司 2022-01-14 CN disclosed
CN-111542590-A Water-soluble unit dose articles comprising perfume 宝洁公司 2020-08-14 CN disclosed
CN-108884424-A Container system with water soluble pouch 宝洁公司 2018-11-23 CN disclosed
CN-107108417-A For making phenols substrate method for hydroxylation 罗地亚经营管理公司 2017-08-29 CN disclosed
US-4908065-A Treating diketone, an element or compound capable of forming complex with the diketone, salts and alkoxide hydrolysates of the elements in aprotic polar solvent TOKYO OHKA KOGYO CO., LTD. (JP) 1990-03-13 US disclosed
US-4900407-A Method for deoxygenation of alcohols YAMASA SHOYU KABUSHIKI KAISHA (JP) 1990-02-13 US disclosed
EP-0238672-A1 PROCESS FOR DEOXIDIZING ALCOHOL Yamasa Shoyu Kabushiki Kaisha (JP) 1987-09-30 EP disclosed
US-4668356-A Photolytic process for the formation of carbon-containing free radicals and its applications to free radical polymerization in particular CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1987-05-26 US disclosed
EP-0141690-A1 Process for the formation of free carbon radicals, its applications, in particular to radical polymerization CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1985-05-15 EP disclosed
US-4072722-A OXIDIZING A MONOHYDRIC PHENOL WITH A KETONE PEROXIDE UBE INDUSTRIES, LTD. (JA) 1978-02-07 US disclosed
US-4013727-A OXIDATION OF PHENYL ETHERS WITH HYDROGEN PEROXIDE UBE INDUSTRIES, LTD. (JA) 1977-03-22 US disclosed