Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15280618 | 0.87 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL15271371 | 0.87 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL16425429 | 0.77 | SRC (0.42) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL23387979 | 0.75 | KDM4C (0.39) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL29901049 | 0.74 | MEN1 (0.36) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL22110813 | 0.73 | KDM4C (0.33) | KDM4CNPC1RAB9A | |
| SCHEMBL12168825 | 0.73 | ICAM1 (0.43) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL9447363 | 0.73 | KDM4C (0.41) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL92936 | 0.72 | L3MBTL1 (0.40) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL8759396 | 0.72 | MEN1 (0.36) | KDM4CNPC1RAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019516-A1 | ASYMMETRIC PHASE TRANSFER CATALYSIS | Merck Sharp & Dohme Corp. (US) | 2022-06-29 | — | — | EP | disclosed |
| EP-2825536-B1 | BIS-QUARTERNARY CINCHONA ALKALOID SALTS AS ASYMMETRIC PHASE TRANSFER CATALYSTS | MERCK SHARP & DOHME (US) | 2020-06-17 | — | — | EP | disclosed |