Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447363 | 0.85 | KDM4C (0.41) | L3MBTL1KDM4CNPC1RAB9AMEN1 | |
| SCHEMBL79915 | 0.85 | L3MBTL1 (0.44) | L3MBTL1HTR2CSLC6A4HTR2AKDM4C | |
| SCHEMBL18355473 | 0.82 | L3MBTL1 (0.38) | L3MBTL1HTR2CSLC6A4HTR2AKDM4C | |
| SCHEMBL14027736 | 0.81 | KDM4C (0.38) | L3MBTL1SLC6A4KDM4CNPC1RAB9A | |
| SCHEMBL5078481 | 0.79 | ALDH1A1 (0.40) | L3MBTL1KDM4CMEN1KMT2AALDH1A1 | |
| SCHEMBL92906 | 0.78 | DRD4 (0.47) | L3MBTL1SLC6A4KDM4CNPC1RAB9A | |
| SCHEMBL26668973 | 0.78 | CXCR3 (0.41) | L3MBTL1HTR2CSLC6A4KDM4CMEN1 | |
| SCHEMBL16425429 | 0.78 | SRC (0.42) | L3MBTL1KDM4CNPC1RAB9AMEN1 | |
| SCHEMBL14065905 | 0.77 | ICAM1 (0.42) | L3MBTL1KDM4CNPC1RAB9AMEN1 | |
| SCHEMBL31615004 | 0.77 | L3MBTL1 (0.38) | L3MBTL1HTR2CSLC6A4KDM4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129361-B2 | Amine compound and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100179216-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179216-A1 | AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF | HLA-B, HLA-A, HLA-C | L3MBTL1 2206/4885HTR2C 1163/4885SLC6A4 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.