Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16782399 | 0.84 | ALDH1A1 (0.44) | THRBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL3064923 | 0.77 | THRB (0.49) | THRBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL11614170 | 0.74 | MEN1 (0.54) | THRBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL2211155 | 0.74 | THRB (0.50) | THRBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL14582771 | 0.73 | THRB (0.42) | THRBALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL8615 | 0.72 | — | — | |
| SCHEMBL478161 | 0.71 | THRB (0.44) | THRBALDH1A1HPGDKDM4EMAPT | |
| Bromide SCHEMBL21060510 | 0.70 | ALDH1A1 (0.42) | THRBALDH1A1HPGDKDM4EMAPT | |
| Selenium SCHEMBL31718132 | 0.70 | ALDH1A1 (0.42) | THRBALDH1A1HPGDKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5155824 | 0.70 | ALDH1A1 (0.42) | THRBALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870156-B1 | PYRIMIDINONE DERIVATIVES AS ANTIMALARIAL AGENTS | SANOFI SA (FR) | 2020-06-17 | — | — | EP | disclosed |