Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CAD | P27708 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870882 | 1.00 | L3MBTL1 (0.79) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL4629331 | 1.00 | L3MBTL1 (0.79) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL30531893 | 0.89 | L3MBTL1 (0.62) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL15730803 | 0.88 | L3MBTL1 (1.00) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL4629356 | 0.87 | L3MBTL1 (0.59) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL4629355 | 0.87 | L3MBTL1 (0.59) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL31228993 | 0.87 | L3MBTL1 (0.60) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL4189292 | 0.87 | L3MBTL1 (0.84) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL4189297 | 0.87 | L3MBTL1 (0.84) | L3MBTL1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL30531875 | 0.86 | L3MBTL1 (0.59) | L3MBTL1KMT2APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666788-A1 | HEMIASTERLIN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES INCLUDING SAME | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |