SCHEMBL4629356

SCHEMBL4629356

CCOC(=O)[C@H](CCC(=O)O)NC(=O)CN

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
KMT2A Q03164 2/20 0.56
POLB P06746 1/20 0.56
NOD1 Q9Y239 4/20 0.48
FOLH1 Q04609 2/20 0.41
RIMKLA Q8IXN7 1/20 0.41
NAALAD2 Q9Y3Q0 1/20 0.41
CAD P27708 1/20 0.41
GABRP O00591 2/20 0.40
GABRD O14764 2/20 0.40
GABRA1 P14867 2/20 0.40
GABRB1 P18505 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
GABRA2 P47869 2/20 0.40
GABRB2 P47870 2/20 0.40
GABRA4 P48169 2/20 0.40
GABRE P78334 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4629355 1.00 L3MBTL1 (0.59) L3MBTL1KMT2APOLBNOD1FOLH1
SCHEMBL3870882 0.87 L3MBTL1 (0.79) L3MBTL1KMT2APOLBNOD1CAD
SCHEMBL4629331 0.87 L3MBTL1 (0.79) L3MBTL1KMT2APOLBNOD1CAD
SCHEMBL22111187 0.87 L3MBTL1 (0.79) L3MBTL1KMT2APOLBNOD1CAD
SCHEMBL25512944 0.86 L3MBTL1 (0.58) L3MBTL1KMT2APOLBNOD1CAD
SCHEMBL28388580 0.85 KMT2A (0.62) L3MBTL1KMT2APOLBNOD1FOLH1
SCHEMBL27761354 0.83 CAD (0.58) L3MBTL1KMT2APOLBNOD1FOLH1
SCHEMBL4628713 0.83 L3MBTL1 (0.46) L3MBTL1KMT2APOLBNOD1CAD
SCHEMBL4628705 0.83 L3MBTL1 (0.46) L3MBTL1KMT2APOLBNOD1CAD
SCHEMBL11124586 0.81 L3MBTL1 (0.56) L3MBTL1KMT2APOLBNOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1618117-B1 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF TRUSTEES EWHA WOMANS UNIVERSIT (KR) 2008-04-23 EP disclosed
EP-1618117-A4 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF TRUSTEES EWHA WOMANS UNIVERSIT (KR) 2007-04-11 EP disclosed
EP-1618117-A1 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF Board of Trustees, Ewha Womans University (KR) 2006-01-25 EP disclosed
US-6951953-B2 Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof EWHA WOMANS UNIVERSITY (KR) 2005-10-04 US disclosed
WO-2004096820-A1 TUMOR SELECTIVE AND BIODEGRADABLE POLYPHOSPHAZENE-PLATINUM(II) CONJUGATE ANTITUMOR AGENT, AND PREPARATION METHOD THEREOF BOARD OF TRUSTEES, EWHA WOMANS UNIVERSITY (KR) 2004-11-11 WO disclosed
US-20040219127-A1 Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof EWHA WOMANS UNIVERSITY (KR) 2004-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040219127-A1 Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof PHOSPHO1, FOLR1, PCNA L3MBTL1 1674/4885KMT2A 1444/4885POLB 404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.