Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22091714 | 0.80 | OPRD1 (0.43) | OPRM1OPRK1OPRD1DRD3HTR7 | |
| SCHEMBL22809117 | 0.80 | OPRD1 (0.67) | OPRM1OPRK1OPRD1CHRM2OPRL1 | |
| SCHEMBL2834966 | 0.78 | OPRL1 (0.61) | OPRM1OPRK1MEN1KMT2AOPRL1 | |
| SCHEMBL22112427 | 0.78 | OPRL1 (0.54) | OPRM1OPRK1LMNAKMT2AOPRL1 | |
| SCHEMBL22112080 | 0.77 | OPRL1 (0.48) | OPRM1OPRK1OPRL1POLBSIGMAR1 | |
| SCHEMBL6601752 | 0.77 | OPRD1 (0.62) | OPRM1OPRK1OPRD1DRD2OPRL1 | |
| SCHEMBL22031589 | 0.75 | OPRD1 (0.60) | OPRM1OPRK1OPRD1CHRM2 | |
| SCHEMBL4813486 | 0.74 | OPRL1 (0.60) | OPRM1OPRD1LMNAOPRL1POLB | |
| SCHEMBL27650580 | 0.74 | PRMT6 (0.58) | DRD2DRD3SIGMAR1 | |
| SCHEMBL6310987 | 0.74 | PRMT6 (0.62) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120539-A1 | NEW PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-06-18 | — | — | WO | disclosed |