SCHEMBL2211224

SCHEMBL2211224

O=C(O)CCCCCC1CO1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.52
LMNA P02545 4/20 0.52
PMP22 Q01453 2/20 0.52
NFKB1 P19838 1/20 0.52
ALDH1A1 P00352 5/20 0.50
GPR84 Q9NQS5 5/20 0.44
FFAR1 O14842 2/20 0.44
FFAR4 Q5NUL3 2/20 0.44
ALOX5 P09917 1/20 0.44
PPARG P37231 6/20 0.43
PPARD Q03181 6/20 0.43
PPARA Q07869 6/20 0.43
HDAC11 Q96DB2 5/20 0.43
TDP1 Q9NUW8 3/20 0.43
HSD17B10 Q99714 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
TLR2 O60603 2/20 0.43
FABP4 P15090 2/20 0.43
ALOX15 P16050 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3681566 1.00 TSHR (0.52) TSHRLMNAPMP22NFKB1ALDH1A1
SCHEMBL28510669 1.00 TSHR (0.52) TSHRLMNAPMP22NFKB1ALDH1A1
SCHEMBL5184107 1.00 TSHR (0.52) TSHRLMNAPMP22NFKB1ALDH1A1
SCHEMBL16330820 1.00 TSHR (0.52) TSHRLMNAPMP22NFKB1ALDH1A1
SCHEMBL1176738 0.98 LMNA (0.50) TSHRLMNAPMP22NFKB1ALDH1A1
SCHEMBL6829630 0.98 LMNA (0.50) TSHRLMNAPMP22NFKB1ALDH1A1
SCHEMBL9235106 0.91
SCHEMBL30936749 0.89 PPARG (0.53) LMNAALDH1A1FFAR1FFAR4PPARG
SCHEMBL10586703 0.87 TSHR (0.43) TSHRLMNAPMP22NFKB1ALDH1A1
SCHEMBL12074895 0.87 TSHR (0.43) TSHRLMNAPMP22NFKB1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103503097-A Metal oxide semiconductor electrode having porous thin film formed thereon, dye-sensitized solar cell using the same, and method for manufacturing the same POSTECH ACAD IND FOUND 2014-01-08 CN claimed
WO-2024102677-A1 CIRCULAR RNA COMPOSITIONS ORNA THERAPEUTICS, INC. (US) 2024-05-16 WO disclosed
EP-4186888-A1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2023-05-31 EP disclosed
US-8815998-B2 Modified natural rubber, production process for the same and rubber composition and tire prepared by using the same BRIDGESTONE CORPORATION (JP) 2014-08-26 US disclosed
EP-2348055-B1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING MODIFIED NATURAL RUBBER, AND RUBBER COMPOSITION AND TIRE USING THE SAME BRIDGESTONE CORP (JP) 2014-02-12 EP disclosed
CN-103503097-A Metal oxide semiconductor electrode having porous thin film formed thereon, dye-sensitized solar cell using the same, and method for manufacturing the same POSTECH ACAD IND FOUND 2014-01-08 CN disclosed
US-20110224365-A1 MODIFIED NATURAL RUBBER, PRODUCTION PROCESS FOR THE SAME AND RUBBER COMPOSITION AND TIRE PREPARED BY USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-09-15 US disclosed
EP-2348055-A1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING MODIFIED NATURAL RUBBER, AND RUBBER COMPOSITION AND TIRE USING THE SAME Bridgestone Corporation (JP) 2011-07-27 EP disclosed
US-7527963-B2 Acetyl-CoA acyltransferase gene disrupted bacterium for producing polyhydroxyalkanoate and method for producing polyhydroxyalkanoate using the same CANON KABUSHIKI KAISHA (JP) 2009-05-05 US disclosed
US-7524659-B2 Isogenic strain line of bacterium for producing polyhydroxyalkanoate in which polyhydroxyalkanoate synthase gene is disrupted and method for producing polyhydroxyalkanoate using the same CANON KABUSHIKI KAISHA (JP) 2009-04-28 US disclosed
US-7235396-B2 Bacterium for producing polyhydroxyalkanoate having polyhydroxyalkanoate depolymerase gene disrupted and method for producing polyhydroxyalkanoate using the same CANON KABUSHIKI KAISHA (JP) 2007-06-26 US disclosed
US-20060172400-A1 Bacterium for producing polyhydroxyalkanoate having polyhydroxyalkanoate depolymerase gene disrupted and method for producing polyhydroxyalkanoate using the same CANON KABUSHIKI KAISHA (JP) 2006-08-03 US disclosed
US-20060172399-A1 Acetyl-CoA acyltransferase gene disrupted bacterium for producing polyhydroxyalkanoate and method for producing polyhydroxyalkanoate using the same CANON KABUSHIKI KAISHA (JP) 2006-08-03 US disclosed
US-20060172398-A1 Isogenic strain line of bacterium for producing polyhydroxyalkanoate in which polyhydroxyalkanoate synthase gene is disrupted and method for producing polyhydroxyalkanoate using the same CANON KABUSHIKI KAISHA (JP) 2006-08-03 US disclosed