Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176738 | 1.00 | LMNA (0.50) | LMNATSHRPMP22NFKB1ALDH1A1 | |
| SCHEMBL5184107 | 0.98 | TSHR (0.52) | LMNATSHRPMP22NFKB1ALDH1A1 | |
| SCHEMBL3681566 | 0.98 | TSHR (0.52) | LMNATSHRPMP22NFKB1ALDH1A1 | |
| SCHEMBL16330820 | 0.98 | TSHR (0.52) | LMNATSHRPMP22NFKB1ALDH1A1 | |
| SCHEMBL2211224 | 0.98 | TSHR (0.52) | LMNATSHRPMP22NFKB1ALDH1A1 | |
| SCHEMBL28510669 | 0.98 | TSHR (0.52) | LMNATSHRPMP22NFKB1ALDH1A1 | |
| SCHEMBL9235106 | 0.93 | — | — | |
| SCHEMBL30936749 | 0.87 | PPARG (0.53) | LMNAALDH1A1HSD17B10TDP1CYP2C9 | |
| SCHEMBL10586703 | 0.85 | TSHR (0.43) | LMNATSHRPMP22NFKB1ALDH1A1 | |
| SCHEMBL12074895 | 0.85 | TSHR (0.43) | LMNATSHRPMP22NFKB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317072-B | Heterocyclic compounds for the treatment of mycobacterial infections and uses thereof | 盟科医药技术(上海)有限公司 | 2020-03-17 | — | — | CN | disclosed |
| US-6740754-B2 | CYCLIZATION OF CARBAMATE WITH SECONDARY ALCOHOL, EPOXIDE OR ESTER REACTANT | PHARMACIA & UPJOHN COMPANY | 2004-05-25 | — | — | US | disclosed |
| EP-0918769-A1 | SUBSTITUTED PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTI-BACTERIAL AGENTS | AstraZeneca AB (SE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0918770-A1 | PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | AstraZeneca AB (SE) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998001446-A1 | SUBSTITUTED PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTI-BACTERIAL AGENTS | ZENECA LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |
| WO-1998001447-A1 | PYRIDYL-PIPERAZINYL-PHENYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | ZENECA LIMITED (GB) | 1998-01-15 | — | — | WO | disclosed |