Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22112044 | 0.88 | ESR2 (0.43) | ESR2CYP26A1DRD2DRD3DRD4 | |
| SCHEMBL22112048 | 0.74 | ESR2 (0.49) | ESR2DRD2DRD3 | |
| SCHEMBL22112254 | 0.69 | ESR2 (0.44) | ESR2 | |
| SCHEMBL22112200 | 0.68 | RIPK1 (0.31) | — | |
| SCHEMBL10931209 | 0.67 | ESR2 (0.49) | ESR2DRD2DRD3DRD4 | |
| SCHEMBL10091140 | 0.66 | ESR2 (0.38) | ESR2 | |
| SCHEMBL22112337 | 0.66 | ALDH1A1 (0.42) | ESR2DRD2DRD3DRD4 | |
| SCHEMBL10931202 | 0.65 | ESR2 (0.44) | ESR2DRD2DRD3DRD4HRH3 | |
| SCHEMBL10930535 | 0.65 | ESR2 (0.50) | ESR2DRD2DRD3DRD4 | |
| SCHEMBL10932075 | 0.65 | ESR2 (0.46) | ESR2DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120539-A1 | NEW PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-06-18 | — | — | WO | disclosed |