SCHEMBL22112697

SCHEMBL22112697

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3cc(-c4ccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)cc4)cc4oc5ccccc5c34)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.35
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 5/20 0.35
POLB P06746 2/20 0.35
CCNC P24863 2/20 0.35
CDK8 P49336 2/20 0.35
MAPT P10636 8/20 0.35
LMNA P02545 5/20 0.35
HPGD P15428 4/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
GLA P06280 1/20 0.35
RECQL P46063 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
KDM1A O60341 1/20 0.34
KMT2A Q03164 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22112381 0.97 TSHR (0.35) TSHRALDH1A1KDM4EPOLBCCNC
SCHEMBL22112382 0.97 TSHR (0.35) TSHRALDH1A1KDM4EPOLBCCNC
SCHEMBL22112392 0.97 TSHR (0.35) TSHRALDH1A1KDM4EPOLBCCNC
SCHEMBL22112395 0.97 TSHR (0.35) TSHRALDH1A1KDM4EPOLBCCNC
SCHEMBL24066137 0.96 ALDH1A1 (0.34) TSHRALDH1A1KDM4EPOLBCCNC
SCHEMBL24255636 0.95 ALDH1A1 (0.35) TSHRALDH1A1KDM4EPOLBMAPT
SCHEMBL22112383 0.94 PLA2G2A (0.37) TSHRALDH1A1KDM4EPOLBCCNC
SCHEMBL22112379 0.93 PLA2G2A (0.36) TSHRALDH1A1KDM4EPOLBCCNC
SCHEMBL26571741 0.92 ALDH1A1 (0.36) TSHRALDH1A1KDM4EPOLBMAPT
SCHEMBL27282726 0.92 CCNC (0.39) ALDH1A1KDM4ECCNCCDK8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020122576-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, METHOD FOR MANUFACTURING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER 엘티소재주식회사 2020-06-18 WO disclosed