Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6852075 | 0.98 | LMNA (0.50) | LMNAMAPTKDM4EALDH1A1GAA | |
| Sulfuric Acid SCHEMBL7811899 | 0.89 | LMNA (0.55) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL8522276 | 0.83 | LMNA (0.51) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL14878651 | 0.83 | GAA (0.58) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL13497807 | 0.82 | LMNA (0.47) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL8218703 | 0.81 | CYP3A4 (0.60) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL2014730 | 0.81 | LMNA (0.50) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL38651108 | 0.81 | CYP3A4 (0.60) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL3784016 | 0.79 | CYP3A4 (0.46) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL27534388 | 0.79 | IDO1 (0.47) | LMNAMAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020120576-A1 | p38α AUTOPHOSPHORYLATION INHIBITORS | FUNDACIÓ INSTITUT DE RECERCA BIOMÈDICA (IRB BARCELONA) (ES) | 2020-06-18 | — | — | WO | disclosed |