⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19564425 | 0.85 | LPAR1 (0.30) | — | |
| SCHEMBL812532 | 0.81 | — | — | |
| SCHEMBL19565193 | 0.80 | PRKCA (0.36) | — | |
| SCHEMBL19543478 | 0.76 | MAPK1 (0.39) | — | |
| SCHEMBL9223886 | 0.72 | PRKCA (0.33) | — | |
| SCHEMBL16384813 | 0.70 | LPAR6 (0.31) | — | |
| SCHEMBL18622399 | 0.70 | MAPK1 (0.31) | — | |
| SCHEMBL19564420 | 0.70 | — | — | |
| SCHEMBL12978409 | 0.70 | MAPK1 (0.42) | — | |
| SCHEMBL9575529 | 0.69 | LPAR6 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332445-B2 | Hydrophilic high quantum yield acridinium esters with improved stability and fast light emission | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20200190037-A1 | HYDROPHILIC HIGH QUANTUM YIELD ACRIDINIUM ESTERS WITH IMPROVED STABILITY AND FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2020-06-18 | — | — | US | disclosed |