Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR6 | P43657 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575513 | 0.87 | — | — | |
| SCHEMBL13541655 | 0.78 | THRB (0.42) | LPAR6LPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL12865190 | 0.78 | LPAR6 (0.35) | LPAR6LPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL9019825 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL12865184 | 0.75 | — | — | |
| SCHEMBL17424512 | 0.75 | — | — | |
| SCHEMBL23171105 | 0.75 | LPAR1 (0.42) | LPAR6LPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL22272342 | 0.75 | LPAR6 (0.31) | LPAR6LPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL14643062 | 0.75 | LPAR6 (0.38) | LPAR6LPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL16384813 | 0.75 | LPAR6 (0.31) | LPAR6LPAR1LPAR4LPAR5LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |