⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30698349 | 1.00 | — | — | |
| SCHEMBL11919201 | 0.86 | ALDH1A1 (0.41) | — | |
| SCHEMBL11916239 | 0.80 | PTPN1 (0.36) | — | |
| SCHEMBL4716113 | 0.77 | TP53 (0.46) | — | |
| SCHEMBL750505 | 0.77 | PLAU (0.37) | — | |
| SCHEMBL2614481 | 0.74 | — | — | |
| SCHEMBL28025218 | 0.74 | GLA (0.41) | — | |
| SCHEMBL16180344 | 0.73 | GABRG2 (0.49) | — | |
| SCHEMBL25404075 | 0.73 | — | — | |
| SCHEMBL30277307 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4729518-A1 | CRYSTAL FORM OF METHIONINE ADENOSYLTRANSFERASE 2A HETEROCYCLIC INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | disclosed |
| CN-121586715-A | Salt and crystal forms of methionine adenosine transferase 2A heterocyclic inhibitor and preparation method thereof | 南京正大天晴制药有限公司 | 2026-02-27 | — | — | CN | disclosed |
| US-20260028365-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC (US) | 2026-01-29 | — | — | US | disclosed |
| WO-2025264837-A1 | NAPHTHYRIDINE GPR52 MODULATORS AND METHODS OF USE THEREOF | LIEBER INSTITUTE, INC. (US) | 2025-12-26 | — | — | WO | disclosed |
| EP-4658659-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | Children's Hospital Medical Center (US) | 2025-12-10 | — | — | EP | disclosed |
| US-20250368648-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-12-04 | — | — | US | disclosed |
| US-12473289-B2 | Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use | AMGEN INC. (US) | 2025-11-18 | — | — | US | disclosed |
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250186444-A1 | METHIONINE ADENOSYLTRANSFERASE 2A HETEROCYCLIC INHIBITOR | NANJING CHIA TAI TIANQING PHARMACEUTICAL CO., LTD. (CN) | 2025-06-12 | — | — | US | disclosed |
| WO-2005033105-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2005-04-14 | — | — | WO | disclosed |
| EP-1506190-A1 | (IMIDAZOL-1-YL-METHYL)-PYRIDAZINE AS NMDA RECEPTOR BLOCKER | F. HOFFMANN-LA ROCHE AG (CH) | 2005-02-16 | — | — | EP | disclosed |
| WO-2004014865-A1 | PHENYLPYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |
| US-20030229096-A1 | Substituted imidazol-pyridazine derivatives | EVOTEC INTERNATIONAL GMBH (DE) | 2003-12-11 | — | — | US | disclosed |
| WO-2003097637-A1 | (IMIDAZOL-1-YL-METHYL)-PYRIDAZINE AS NMDA RECEPTOR BLOCKER | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-27 | — | — | WO | disclosed |
| US-5623072-A | CONTROLLING WEED; CROP TOLERANCE | MONSANTO COMPANY (US) | 1997-04-22 | — | — | US | disclosed |
| US-5616789-A | CHEMICAL INTERMEDIATE FOR 2-PHENYLPYRIDAZINE HERBICIDE | MONSANTO COMPANY (US) | 1997-04-01 | — | — | US | disclosed |
| US-5559080-A | 3-phenoxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| US-5536701-A | 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof | MONSANTO COMPANY (US) | 1996-07-16 | — | — | US | disclosed |
| US-5484761-A | PRE OR POSTEMERGENT HERBICIDES | MONSANTO COMPANY (US) | 1996-01-16 | — | — | US | disclosed |