Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.53 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23938434 | 0.94 | KDM4E (0.47) | LPLLIPGKDM4ECYP3A4MAPT | |
| SCHEMBL8491487 | 0.86 | KDM4E (0.50) | KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL8518305 | 0.86 | LPL (0.66) | LPLLIPGKDM4ECYP3A4L3MBTL1 | |
| SCHEMBL8098362 | 0.84 | LPL (0.59) | LPLLIPGCYP3A4L3MBTL1TDP1 | |
| SCHEMBL4032533 | 0.84 | LPL (0.67) | LPLLIPGKDM4ECYP3A4PPARG | |
| SCHEMBL10518886 | 0.84 | LPL (0.67) | LPLLIPGKDM4ECYP3A4PPARG | |
| SCHEMBL9420947 | 0.84 | LPL (0.63) | LPLLIPGKDM4ECYP3A4L3MBTL1 | |
| SCHEMBL29742685 | 0.84 | LPL (0.67) | LPLLIPGKDM4ECYP3A4PPARG | |
| SCHEMBL5249436 | 0.84 | LPL (0.67) | LPLLIPGKDM4ECYP3A4PPARG | |
| SCHEMBL6932623 | 0.84 | LPL (0.67) | LPLLIPGKDM4ECYP3A4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123670-A1 | SMALL MOLECULE INHIBITORS OF THE ANDROGEN RECEPTOR ACTIVITY AND/OR EXPRESSION AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2020-06-18 | — | — | WO | disclosed |