Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 6/20 | 0.46 |
| ▸ | LPL | P06858 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22113441 | 0.94 | LPL (0.53) | KDM4ECYP3A4MAPTPRMT6LPL | |
| SCHEMBL8491487 | 0.88 | KDM4E (0.50) | KDM4ECYP3A4MAPTPRMT6NOS1 | |
| SCHEMBL347126 | 0.85 | LPL (0.57) | LPLLIPGXIAP | |
| SCHEMBL3052902 | 0.85 | TAAR1 (0.59) | KDM4EMAPTLPLLIPGNOS1 | |
| SCHEMBL5433566 | 0.84 | LPL (0.52) | LPLLIPGXIAP | |
| SCHEMBL1697126 | 0.83 | MAPT (0.64) | KDM4ECYP3A4MAPTPRMT6NOS1 | |
| SCHEMBL28141752 | 0.81 | LPL (0.63) | CYP3A4LPLLIPGXIAP | |
| SCHEMBL28409443 | 0.81 | LPL (0.53) | LPLLIPGXIAP | |
| Hydrochloric Acid SCHEMBL3273205 | 0.81 | MAPT (0.68) | KDM4ECYP3A4MAPTPRMT6NOS1 | |
| SCHEMBL8094986 | 0.80 | LPL (0.49) | LPLLIPGXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3297438-B1 | CCR2 MODULATORS | CHEMOCENTRYX INC (US) | 2021-10-20 | — | — | EP | disclosed |