Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19290268 | 0.83 | OPRM1 (0.38) | DNM1OPRM1SPHK1LMNA | |
| SCHEMBL22327703 | 0.77 | GBA1 (0.32) | GBA1 | |
| SCHEMBL21226122 | 0.77 | GNAI3 (0.39) | DNM1 | |
| SCHEMBL23717596 | 0.77 | GNAI3 (0.39) | DNM1 | |
| SCHEMBL24822691 | 0.77 | GNAI3 (0.39) | DNM1 | |
| Iodide SCHEMBL15008388 | 0.76 | GNAI3 (0.38) | DNM1 | |
| Iodide SCHEMBL15008245 | 0.76 | GNAI3 (0.38) | DNM1 | |
| Iodide SCHEMBL15008673 | 0.76 | GNAI3 (0.38) | DNM1 | |
| Iodide SCHEMBL15008368 | 0.76 | GNAI3 (0.38) | DNM1 | |
| Iodide SCHEMBL15008980 | 0.76 | GNAI3 (0.38) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403495-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2021-12-30 | — | — | US | disclosed |
| US-20200190126-A1 | Inhibitors of Cyclin-Dependent Kinase 7 (CDK7) | MEDIC LIFE SCIENCES, INC. | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403495-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, CDK1, CDK17 | DNM1 2816/4885OPRM1 4366/4885SPHK1 1448/4885 |
| US-20200190126-A1 | Inhibitors of Cyclin-Dependent Kinase 7 (CDK7) | CDK7, CDK1, CDK17 | DNM1 2816/4885OPRM1 4366/4885SPHK1 1448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.