SCHEMBL22115306

SCHEMBL22115306

N#Cc1ccccc1-c1cc(Cl)ccc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 2/20 0.43
CYP11B1 P15538 1/20 0.43
GABRG2 P18507 6/20 0.43
GABRB3 P28472 6/20 0.43
GABRA3 P34903 6/20 0.43
GABRA1 P14867 5/20 0.43
GABRA5 P31644 3/20 0.43
GABRA2 P47869 1/20 0.42
ESR2 Q92731 1/20 0.41
FPR1 P21462 1/20 0.39
FPR2 P25090 1/20 0.39
S100A4 P26447 1/20 0.39
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
AR P10275 1/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19579267 0.83 ESR2 (0.47) CYP11B2CYP11B1GABRG2GABRB3GABRA3
SCHEMBL19579215 0.81 ALOX5AP (0.46) CYP11B2CYP11B1GABRG2GABRB3GABRA3
SCHEMBL2648329 0.81 GABRA1 (0.44) CYP11B2CYP11B1GABRG2GABRB3GABRA3
SCHEMBL2651126 0.81 ALOX5AP (0.44) CYP11B2CYP11B1GABRG2GABRB3GABRA3
SCHEMBL2650416 0.81 ESR2 (0.48) CYP11B2CYP11B1GABRG2GABRB3GABRA3
SCHEMBL28568884 0.79 CYP11B1 (0.51) CYP11B2CYP11B1GABRG2GABRB3GABRA3
SCHEMBL19579264 0.79 USP8 (0.47) CYP11B2CYP11B1GABRG2GABRB3GABRA3
SCHEMBL9069185 0.79 ESR2 (0.47) CYP11B2CYP11B1GABRG2GABRB3GABRA3
SCHEMBL31067119 0.78 HSD11B1 (0.49) GABRG2GABRB3GABRA3GABRA1GABRA5
SCHEMBL20898552 0.78 HSD11B1 (0.49) GABRG2GABRB3GABRA3GABRA1GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3670507-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2026-05-06 EP disclosed
EP-3670507-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-06-24 EP disclosed
EP-3670507-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-06-24 EP disclosed