SCHEMBL22115307

SCHEMBL22115307

N#Cc1ccccc1-c1ccc(F)c(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 4/20 0.52
PTGS2 P35354 3/20 0.50
AR P10275 2/20 0.50
PTGS1 P23219 2/20 0.50
ESR2 Q92731 1/20 0.50
ALOX5AP P20292 1/20 0.49
FEN1 P39748 1/20 0.49
TRPA1 O75762 1/20 0.46
NR3C1 P04150 1/20 0.44
PTPN5 P54829 1/20 0.43
CYP11B1 P15538 2/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
HSD17B3 P37058 1/20 0.42
ACHE P22303 1/20 0.41
IDO1 P14902 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6562393 0.80 ESR2 (0.50) CYP11B2ARESR2TRPA1HSD17B3
SCHEMBL6218205 0.80 ESR2 (0.50) CYP11B2ARESR2ALOX5APFEN1
SCHEMBL2653323 0.80 ALOX5AP (0.56) CYP11B2ARESR2ALOX5APFEN1
SCHEMBL4000273 0.80 CYP11B2 (0.64) CYP11B2PTGS2ARALOX5APFEN1
SCHEMBL29662920 0.80 ESR2 (0.50) CYP11B2ARESR2TRPA1HSD17B3
SCHEMBL2656616 0.80 AR (0.61) CYP11B2ARALOX5APFEN1CYP11B1
SCHEMBL15832014 0.80 CYP11B2 (0.46) CYP11B2PTGS2ARPTGS1CYP11B1
SCHEMBL19955381 0.80 CYP11B2 (0.49) CYP11B2CYP11B1CNR1CNR2
SCHEMBL6562156 0.80 AR (0.65) CYP11B2ARESR2TRPA1PTPN5
SCHEMBL1541402 0.78 ESR2 (0.66) PTGS2PTGS1ESR2TRPA1PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3670507-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2026-05-06 EP disclosed
EP-3670507-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-06-24 EP disclosed
EP-3670507-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-06-24 EP disclosed