Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 10/20 | 0.77 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422888 | 0.95 | STS (0.70) | STSGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL28422820 | 0.87 | STS (0.80) | STSGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL22089512 | 0.87 | STS (0.80) | STSGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL1970651 | 0.87 | STS (1.00) | STSGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL22089514 | 0.85 | STS (0.77) | STSGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL3929382 | 0.84 | GPR119 (0.56) | STSGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL22089505 | 0.82 | STS (0.90) | STSGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL28418216 | 0.82 | STS (0.90) | STSGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL22089534 | 0.81 | STS (1.00) | STSPTPN2PTPN1PTPN6KMT2A | |
| SCHEMBL3146175 | 0.79 | GPR119 (0.60) | STSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119590-A1 | 3-CYANOPYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USES THEREOF. | 中国科学院上海药物研究所 | 2020-06-18 | — | — | WO | disclosed |