Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.56 |
| ▸ | STS | P08842 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.52 |
| ▸ | OGA | O60502 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984198 | 0.88 | HDAC1 (0.54) | GPR119ALDH1A1LMNAEPHX2NPSR1 | |
| SCHEMBL8266055 | 0.85 | GPR119 (0.57) | GPR119STSALDH1A1PTPN2PTPN1 | |
| SCHEMBL1668815 | 0.85 | SMN1; SMN2 (0.52) | GPR119ALDH1A1LMNAEPHX2NPSR1 | |
| SCHEMBL171943 | 0.85 | STS (0.64) | STSALDH1A1LMNAEPHX2PTPN2 | |
| SCHEMBL12804554 | 0.85 | NPSR1 (0.68) | GPR119STSALDH1A1LMNAEPHX2 | |
| SCHEMBL30924055 | 0.84 | EPHX2 (0.58) | GPR119STSALDH1A1EPHX2PTPN2 | |
| SCHEMBL27022355 | 0.84 | ALDH1A1 (0.71) | STSALDH1A1LMNAEPHX2KMT2A | |
| SCHEMBL22115706 | 0.84 | STS (0.77) | GPR119STSPTPN2PTPN1PTPN6 | |
| SCHEMBL20116384 | 0.83 | GPR119 (0.47) | GPR119ALDH1A1LMNAEPHX2NPSR1 | |
| SCHEMBL13111226 | 0.83 | ALDH1A1 (0.51) | GPR119ALDH1A1LMNAEPHX2OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009010480-A1 | 1-{2-[(DIPHENYL)AMINO]-ETHYL}-PIPERIDINE-4-CARBOXYLIC ACID BENZYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS CCR5 AGONISTS FOR THE TREATMENT OF IMMUNE AND INFLAMMATORY DISEASES | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |