Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22116059 | 0.92 | BRD4 (0.46) | BRD9BRD4KDM4EALDH1A1HPGD | |
| SCHEMBL22116021 | 0.85 | BRD4 (0.49) | BRD9BRD4KDM4EALDH1A1HPGD | |
| 1-Bromobutane SCHEMBL22116093 | 0.80 | BRD4 (0.44) | BRD9BRD4KDM4EALDH1A1HPGD | |
| SCHEMBL22116007 | 0.77 | BRD4 (0.51) | BRD9BRD4KDM4EALDH1A1HPGD | |
| SCHEMBL22116110 | 0.74 | BRD4 (0.69) | BRD9BRD4CREBBPPTK2BRDT | |
| SCHEMBL18190690 | 0.71 | ALDH1A1 (0.46) | BRD4KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL744649 | 0.66 | PTK2 (0.61) | BRD4ALDH1A1PTK2LMNAMAPT | |
| SCHEMBL22116063 | 0.63 | BRD4 (0.94) | BRD9BRD4KDM4EALDH1A1HPGD | |
| SCHEMBL5349652 | 0.63 | ALDH1A1 (0.54) | BRD9KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL8525719 | 0.62 | PTK2 (0.65) | BRD4ALDH1A1CYP1A2CYP2C9PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898587-B1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | UNIV FREIBURG ALBERT LUDWIGS (DE) | 2024-06-26 | — | — | EP | disclosed |
| US-20220055989-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | ALBERT LUDWING UNIV FREIBURG (DE) | 2022-02-24 | — | — | US | disclosed |
| EP-3898587-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | Albert-Ludwigs-Universität Freiburg (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020127846-A9 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | ALBERT LUDWIG UNIVERSITÄT FREIBURG (DE) | 2021-08-12 | — | — | WO | disclosed |
| WO-2020127846-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | ALBERT LUDWIG UNIVERSITÄT FREIBURG (DE) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220055989-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | BRD4, BRPF3, BRD2 | BRD9 14/4885BRD4 1/4885KDM4E 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.