Mesotrione

Mesotrione

SCHEMBL22116

CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c([N+](=O)[O-])c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPD P32754 1/20 0.62
ALDH3A1 P30838 3/20 0.46
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mesotrione SCHEMBL29352201 1.00 HPD (0.62) HPDALDH3A1ALDH1A1MEN1KMT2A
Mesotrione SCHEMBL4895947 1.00 HPD (0.62) HPDALDH3A1ALDH1A1MEN1KMT2A
Mesotrione SCHEMBL2503425 0.99 HPD (0.61) HPDALDH3A1ALDH1A1MEN1KMT2A
Mesotrione SCHEMBL20723476 0.99 HPD (0.61) HPDALDH3A1ALDH1A1MEN1KMT2A
Mesotrione SCHEMBL2233142 0.99 HPD (0.61) HPDALDH3A1ALDH1A1MEN1KMT2A
Mesotrione SCHEMBL1667345 0.99 HPD (0.61) HPDALDH3A1ALDH1A1MEN1KMT2A
Mesotrione SCHEMBL1162075 0.99 HPD (0.61) HPDALDH3A1ALDH1A1MEN1KMT2A
Mesotrione SCHEMBL22720520 0.97 HPD (0.60) HPDALDH3A1ALDH1A1MEN1KMT2A
Mesotrione SCHEMBL16115701 0.96 HPD (0.59) HPDALDH3A1ALDH1A1MEN1KMT2A
Mesotrione SCHEMBL366882 0.95 HPD (0.58) HPDALDH3A1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 27045 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144260-A1 COMPOSITION AND METHOD FOR IMPROVING AGRONOMIC TRAITS OF A PLANT THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2026-05-28 US claimed
CN-117322426-B Compound herbicide and preparation method and application thereof Jilin Academy of Agricultural Sciences (China Agricultural Science and Technology Northeast Innovation Center) (CN) 2026-05-26 CN claimed
CN-122030399-A Preparation method of herbicide containing mesotrione, triclopyr and halosulfuron-methyl Long Ganzhe field 山东胜邦绿野化学有限公司 2026-05-15 CN claimed
CN-122038380-A DNA shuffling method based on flanking sequence segmented amplification and application thereof in screening herbicide resistance hybrid enzyme 江苏省农业科学院 2026-05-15 CN claimed
EP-4740733-A1 COMPOSITIONS OF ADJUVANTS AND COSOLVENTS FOR IMPROVING PENETRATION OF HERBICIDES AND/OR FERTILISERS THROUGH SURFACES OF ABOVEGROUND PARTS OF PLANT ORGANS. Uniwersystet Slaski w Katowicach (PL) 2026-05-13 EP claimed
CN-122004229-A Ternary weeding composition and application thereof 山东清原农冠作物科学有限公司 2026-05-12 CN claimed
CN-122017081-A Method for detecting 12 hppd inhibitor herbicides in plant-derived food 伊宁海关技术中心 2026-05-12 CN claimed
CN-122004216-A Herbicide composition containing cyclohexene diketone lactic acid oxime ether derivative and application thereof 郑州手性药物研究院有限公司 2026-05-12 CN claimed
US-12616200-B2 Herbicidal combinations comprising diflufenican and mesotrione BAYER AKTIENGESELLSCHAFT (DE) 2026-05-05 US claimed
US-12616201-B2 Herbicidal compositions comprising isoxaflutole BASF SE (DE) 2026-05-05 US claimed
US-5912207-A HEAT STABLE, CHEMICALLY STABLE HERBICIDES ZENECA LIMITED (GB) 1999-06-15 US claimed
WO-1999023886-A1 METHOD OF CONTROLLING WEEDS IN TRANSGENIC CROPS AVENTIS CROPSCIENCE S.A. (FR) 1999-05-20 WO claimed
EP-0756452-B1 SYNERGISTIC HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF ZENECA LTD (GB) 1999-05-12 EP claimed
EP-0840548-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF ZENECA LIMITED (GB) 1998-05-13 EP claimed
US-5741756-A MIXTURES WITH 2-(2'-NITRO-4'METHYLSULFONYLBENZOYL)-1,3-CYCLOHEXANEDIONE ZENECA LIMITED (GB) 1998-04-21 US claimed
US-5698493-A MIXTURE OF ATRAZINE AND 2-(2'-NITRO-4'-METHYLSULFONYLBENZOYL)-1,3-CYCLOHEXANEDIONE OR THE CORRESPONDING METHYLSULFONYLOXY DERIVATIVE ZENECA LIMITED (GB) 1997-12-16 US claimed
WO-1997003562-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF ZENECA LIMITED (GB) 1997-02-06 WO claimed
EP-0756452-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF ZENECA LIMITED (GB) 1997-02-05 EP claimed
US-5506195-A 2-(2'-NITRO-4'-METHYLSULFONYLBENZOYL)-1,3-CYCLOHEXANEDIOL APPLIED AS PREEMERGENCE OR POSTEMERGENCE HERBICIDE FOR CONTROLLING UNDESIRABLE VEGETATION ZENECA LIMITED (GB) 1996-04-09 US claimed
WO-1995028839-A1 SYNERGISTIC HERBICIDAL COMPOSITION AND METHOD OF USE THEREOF ZENECA LIMITED (GB) 1995-11-02 WO claimed