Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117340 | 1.00 | ALDH1A1 (0.32) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL11096588 | 0.82 | ALDH1A1 (0.34) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL11096585 | 0.82 | ALDH1A1 (0.34) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL11706677 | 0.79 | — | — | |
| SCHEMBL11706685 | 0.79 | — | — | |
| SCHEMBL27487247 | 0.78 | — | — | |
| SCHEMBL504504 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL504505 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL1658557 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHR | |
| SCHEMBL1658556 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897677-A1 | COMPOSITION FOR USE IN A METHOD FOR LOWERING OF LDL-CHOLESTEROL IN PLASMA | ezCol B.V. (NL) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020130813-A1 | COMPOSITION FOR USE IN A METHOD FOR LOWERING OF LDL-CHOLESTEROL IN PLASMA | EZCOL B.V. (NL) | 2020-06-25 | — | — | WO | disclosed |