SCHEMBL504505

SCHEMBL504505

COC(C)(C)C/C=C/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C=C(C)/C=C/CC(C)(C)OC

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 2/20 0.38
RECQL P46063 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TSHR P16473 1/20 0.38
PTGS1 P23219 1/20 0.37
LMNA P02545 2/20 0.37
NR1I2 O75469 1/20 0.37
PGR P06401 1/20 0.37
PTPN1 P18031 1/20 0.33
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL504504 1.00 ALDH1A1 (0.39) ALDH1A1TDP1KDM4EMAPTALOX15
SCHEMBL22117353 0.93 ALDH1A1 (0.35) ALDH1A1TDP1KDM4EMAPTALOX15
SCHEMBL29885271 0.88 ALDH1A1 (0.35) ALDH1A1TDP1KDM4EMAPTALOX15
SCHEMBL2837930 0.85 LMNA (0.41) ALDH1A1TDP1KDM4EMAPTLMNA
SCHEMBL2840811 0.84 NR1I2 (0.66) ALDH1A1ALOX15LMNANR1I2PGR
SCHEMBL2831023 0.83 PTGS1 (0.40) ALDH1A1TDP1KDM4EMAPTALOX15
SCHEMBL39362 0.83 NR1I2 (0.39) LMNANR1I2PGR
SCHEMBL504503 0.83 NR1I2 (0.39) LMNANR1I2PGR
SCHEMBL116111 0.82 NR1I2 (0.62) ALDH1A1MAPTALOX15LMNANR1I2
SCHEMBL2838750 0.82 NR1I2 (0.62) ALDH1A1MAPTALOX15LMNANR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250601-A1 MICROBIAL PRODUCTION OF PROTEIN AND PHB BY ALCOHOL UTILIZING BACTERIA KNIPBIO INC (US) 2025-08-07 US claimed
WO-2023224042-A1 PACKAGED FOOD OR BEVERAGE, METHOD OF PRODUCING PACKAGED FOOD OR BEVERAGE, USE OF XANTHOPHYLL IN PRODUCTION OF PACKAGED FOOD OR BEVERAGE, AND ORAL COMPOSITION SUNTORY HOLDINGS LIMITED (JP) 2023-11-23 WO claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
US-11603549-B2 Biological devices and methods of use thereof to produce carotenoids Bio Capital Holdings, LLC (US) 2023-03-14 US claimed
EP-3897677-A1 COMPOSITION FOR USE IN A METHOD FOR LOWERING OF LDL-CHOLESTEROL IN PLASMA ezCol B.V. (NL) 2021-10-27 EP claimed
US-20210275601-A1 LDL-CHOLESTEROL-LOWERING CELL EXTRACT AND FOOD SUPPLEMENT EZCOL B.V. (NL) 2021-09-09 US claimed
US-11026981-B2 LDL-cholesterol-lowering cell extract and food supplement EZCOL B.V. (NL) 2021-06-08 US claimed
US-10920230-B2 Methylotrophs for aquaculture and animal feed KNIPBIO, INC. (US) 2021-02-16 US claimed
US-20200270667-A1 BIOLOGICAL DEVICES AND METHODS OF USE THEREOF TO PRODUCE CAROTENOIDS Bio Capital Holdings, LLC (US) 2020-08-27 US claimed
WO-2020130813-A1 COMPOSITION FOR USE IN A METHOD FOR LOWERING OF LDL-CHOLESTEROL IN PLASMA EZCOL B.V. (NL) 2020-06-25 WO claimed
US-20040219629-A1 Increasing carotenoid production in bacteria via chromosomal integration E.I. DU PONT DE NEMOURS AND COMPANY 2004-11-04 US claimed
US-20040209365-A1 Parallel chromosomal stacking of traits in bacteria E. I. DU PONT DE NEMOURS AND COMPANY 2004-10-21 US claimed
US-20040146966-A1 Mutations affecting carotenoid production E.I. DU PONT DE NEMOURS AND COMPANY 2004-07-29 US claimed
WO-2004056975-A2 INCREASING CAROTENOID PRODUCTION IN BACTERIA VIA CHROMOSOMAL INTEGRATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-07-08 WO claimed
WO-2004056972-A2 PARALLEL CHROMOSOMAL STACKING OF TRAITS IN BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-07-08 WO claimed
WO-2004056974-A2 MUTATIONS AFFECTING CAROTENOID PRODUCTION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-07-08 WO claimed
US-20040077068-A1 Use of microorganisms which metabolize single carbon substrates for the production of carotenoid compounds in high yields E.I. DU PONT DE NEMOURS AND COMPANY 2004-04-22 US claimed
EP-1328639-A2 CAROTENOID PRODUCTION BY RECOMBINANT, C1-METABOLIZING METHANOTROPHIC BACTERIA E.I. DUPONT DE NEMOURS AND COMPANY (US) 2003-07-23 EP claimed
US-20030003528-A1 Carotenoid production from a single carbon substrate E. I. DU PONT DE NEMOURS AND COMPANY 2003-01-02 US claimed
WO-2002018617-A2 CAROTENOID PRODUCTION BY RECOMBINANT, C1-METABOLIZING METHANOTHROPIC BACTERIA E.I. DUPONT DE NEMOURS AND COMPANY (US) 2002-03-07 WO claimed