Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NRP1 | O14786 | 2/20 | 0.32 |
| ▸ | NPY4R | P50391 | 4/20 | 0.32 |
| ▸ | NPY1R | P25929 | 2/20 | 0.32 |
| ▸ | NPY2R | P49146 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.32 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117398 | 1.00 | SIRT5 (0.38) | SIRT5NOD1SMN1; SMN2NRP1NPY4R | |
| SCHEMBL22117375 | 0.88 | SIRT5 (0.39) | SIRT5NOD1NRP1NPY4RNPY1R | |
| SCHEMBL22117374 | 0.88 | SIRT5 (0.39) | SIRT5NOD1NRP1NPY4RNPY1R | |
| SCHEMBL31679028 | 0.82 | DPP8 (0.49) | CPB2 | |
| SCHEMBL22117551 | 0.80 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL22117553 | 0.80 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL22117468 | 0.75 | SIRT5 (0.38) | SIRT5NOD1CPB2NMT2NMT1 | |
| SCHEMBL22117465 | 0.75 | SIRT5 (0.38) | SIRT5NOD1CPB2NMT2NMT1 | |
| SCHEMBL14739594 | 0.72 | SIRT5 (0.46) | SIRT5NOD1SMN1; SMN2TLR2ALB | |
| SCHEMBL31679031 | 0.71 | DPP8 (0.51) | CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898652-A1 | MITOCHONDRIA-TARGETING PEPTIDES | Stealth Biotherapeutics Corp (MC) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020131282-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |