SCHEMBL31679031

SCHEMBL31679031

NC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)[C@@H](N)CC12CC(C1)C2

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ DPP8 Q6V1X1 3/20 0.51
▸ DPP7 Q9UHL4 3/20 0.51
▸ CTSL P07711 1/20 0.51
▸ SIRT2 Q8IXJ6 1/20 0.51
▸ FOLH1 Q04609 2/20 0.50
▸ ANPEP P15144 1/20 0.49
▸ DPP4 P27487 2/20 0.48
▸ DPP9 Q86TI2 2/20 0.48
▸ CPB1 P15086 1/20 0.47
▸ CPB2 Q96IY4 1/20 0.47
▸ CA1 P00915 1/20 0.46
▸ CA2 P00918 1/20 0.46
▸ MMP2 P08253 1/20 0.46
▸ MMP9 P14780 1/20 0.46
▸ PTGER4 P35408 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26212052 0.96 DPP8 (0.49) DPP8DPP7CTSLSIRT2FOLH1
SCHEMBL31679028 0.91 DPP8 (0.49) DPP8DPP7CTSLSIRT2FOLH1
SCHEMBL31679020 0.91 CTSL (0.53) CTSLPTGER4
SCHEMBL22117406 0.90 SIRT2 (0.50) DPP8DPP7CTSLSIRT2FOLH1
SCHEMBL22117407 0.90 SIRT2 (0.50) DPP8DPP7CTSLSIRT2FOLH1
SCHEMBL31679017 0.87 CTSL (0.49) CTSLSIRT2PTGER4
SCHEMBL17073781 0.85 CTSL (0.63) DPP8DPP7CTSLSIRT2FOLH1
SCHEMBL31679027 0.83 KMT2A (0.48) CTSLSIRT2FOLH1
SCHEMBL30341837 0.83 KLK7 (0.54) CTSLSIRT2
SCHEMBL22117557 0.82 CTSL (0.51) CTSLSIRT2PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404300-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2025-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404300-B2 Mitochondria-targeting peptides SSBP1, HSPE1, IMMT DPP8 1568/4885DPP7 1306/4885CTSL 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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