SCHEMBL22117451

SCHEMBL22117451

CC(C)(C)OC(=O)N[C@@H](CC12CC3CC(CC(C3)C1)C2)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCNC(=O)O)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PSMB8 P28062 1/20 0.46
▸ PSMB9 P28065 1/20 0.46
▸ PSMB5 P28074 1/20 0.46
▸ CCKBR P32239 2/20 0.45
▸ NPFFR1 Q9GZQ6 1/20 0.45
▸ NPFFR2 Q9Y5X5 1/20 0.45
▸ REN P00797 2/20 0.45
▸ CCKAR P32238 1/20 0.44
▸ ERAP2 Q6P179 2/20 0.44
▸ ERAP1 Q9NZ08 2/20 0.44
▸ LNPEP Q9UIQ6 2/20 0.44
▸ NPY4R P50391 3/20 0.43
▸ NPY1R P25929 2/20 0.43
▸ NPY2R P49146 2/20 0.43
▸ NPY5R Q15761 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22117454 1.00 PSMB8 (0.46) PSMB8PSMB9PSMB5CCKBRNPFFR1
SCHEMBL22133070 0.94 NPFFR1 (0.45) PSMB8PSMB9PSMB5CCKBRNPFFR1
SCHEMBL22133064 0.94 NPFFR1 (0.45) PSMB8PSMB9PSMB5CCKBRNPFFR1
SCHEMBL30341836 0.94 PSMB8 (0.47) PSMB8PSMB9PSMB5CCKBRNPFFR1
SCHEMBL30341831 0.93 KLK7 (0.49) PSMB8PSMB9PSMB5CCKBRNPFFR1
SCHEMBL31679039 0.93 KLK7 (0.49) PSMB8PSMB9PSMB5CCKBRNPFFR1
SCHEMBL28633963 0.92 NPFFR1 (0.43) PSMB8PSMB9PSMB5CCKBRNPFFR1
SCHEMBL28633961 0.92 NPFFR1 (0.43) PSMB8PSMB9PSMB5CCKBRNPFFR1
SCHEMBL22117564 0.92 PSMB8 (0.46) PSMB8PSMB9PSMB5CCKBRREN
SCHEMBL22117567 0.92 PSMB8 (0.46) PSMB8PSMB9PSMB5CCKBRREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3898652-A1 MITOCHONDRIA-TARGETING PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-10-27 — — EP disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed
Send feedback