SCHEMBL22117564

CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC12CCC(CC1)CC2)C(=O)N[C@@H](CCCCNC(=O)O)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PSMB8	P28062	1/20	0.46

▸	PSMB9	P28065	1/20	0.46

▸	PSMB5	P28074	1/20	0.46

▸	CCKBR	P32239	2/20	0.45

▸	REN	P00797	2/20	0.45

▸	CCKAR	P32238	1/20	0.44

▸	NPY4R	P50391	5/20	0.43

▸	NPY1R	P25929	2/20	0.43

▸	NPY2R	P49146	2/20	0.43

▸	NPY5R	Q15761	2/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22117567	1.00	PSMB8 (0.46)	PSMB8PSMB9PSMB5CCKBRREN
SCHEMBL31679030	0.93	KLK7 (0.49)	PSMB8PSMB9PSMB5CCKBRNPY4R
SCHEMBL22117451	0.92	PSMB8 (0.46)	PSMB8PSMB9PSMB5CCKBRREN
SCHEMBL22117454	0.92	PSMB8 (0.46)	PSMB8PSMB9PSMB5CCKBRREN
SCHEMBL22117421	0.90	REN (0.54)	CCKBRRENNPY4RNPY1RNPY2R
SCHEMBL22117422	0.90	REN (0.54)	CCKBRRENNPY4RNPY1RNPY2R
SCHEMBL22117551	0.87	NPY4R (0.47)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL22117553	0.87	NPY4R (0.47)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL31679025	0.86	KLK7 (0.50)	PSMB8PSMB9PSMB5CCKBRNPY4R
SCHEMBL22133064	0.86	NPFFR1 (0.45)	PSMB8PSMB9PSMB5CCKBRREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3898652-A1	MITOCHONDRIA-TARGETING PEPTIDES	Stealth Biotherapeutics Corp (MC)	2021-10-27	—	—	EP	disclosed
WO-2020131282-A1	MITOCHONDRIA-TARGETING PEPTIDES	STEALTH BIOTHERAPEUTICS CORP. (MC)	2020-06-25	—	—	WO	disclosed