Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | CCKAR | P32238 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 5/20 | 0.43 |
| ▸ | NPY1R | P25929 | 2/20 | 0.43 |
| ▸ | NPY2R | P49146 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117564 | 1.00 | PSMB8 (0.46) | PSMB8PSMB9PSMB5CCKBRREN | |
| SCHEMBL31679030 | 0.93 | KLK7 (0.49) | PSMB8PSMB9PSMB5CCKBRNPY4R | |
| SCHEMBL22117451 | 0.92 | PSMB8 (0.46) | PSMB8PSMB9PSMB5CCKBRREN | |
| SCHEMBL22117454 | 0.92 | PSMB8 (0.46) | PSMB8PSMB9PSMB5CCKBRREN | |
| SCHEMBL22117421 | 0.90 | REN (0.54) | CCKBRRENNPY4RNPY1RNPY2R | |
| SCHEMBL22117422 | 0.90 | REN (0.54) | CCKBRRENNPY4RNPY1RNPY2R | |
| SCHEMBL22117551 | 0.87 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL22117553 | 0.87 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31679025 | 0.86 | KLK7 (0.50) | PSMB8PSMB9PSMB5CCKBRNPY4R | |
| SCHEMBL22133064 | 0.86 | NPFFR1 (0.45) | PSMB8PSMB9PSMB5CCKBRREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898652-A1 | MITOCHONDRIA-TARGETING PEPTIDES | Stealth Biotherapeutics Corp (MC) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020131282-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |