Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117499 | 1.00 | SIRT2 (0.49) | SIRT2CTSLFOLH1CA1CA2 | |
| SCHEMBL22117406 | 0.91 | SIRT2 (0.50) | SIRT2CTSLFOLH1CA1CA2 | |
| SCHEMBL22117407 | 0.91 | SIRT2 (0.50) | SIRT2CTSLFOLH1CA1CA2 | |
| SCHEMBL31679028 | 0.90 | DPP8 (0.49) | SIRT2CTSLFOLH1CA1CA2 | |
| SCHEMBL31679036 | 0.90 | KLK7 (0.54) | SIRT2CTSLCA1CA2 | |
| SCHEMBL31679013 | 0.87 | NPY4R (0.48) | SIRT2CTSLPTGER4 | |
| SCHEMBL22117556 | 0.83 | CTSL (0.51) | SIRT2CTSLPTGER4 | |
| SCHEMBL22117557 | 0.83 | CTSL (0.51) | SIRT2CTSLPTGER4 | |
| SCHEMBL22117811 | 0.83 | CTSL (0.51) | SIRT2CTSLPTGER4 | |
| SCHEMBL22117808 | 0.83 | CTSL (0.51) | SIRT2CTSLPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898652-A1 | MITOCHONDRIA-TARGETING PEPTIDES | Stealth Biotherapeutics Corp (MC) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020131282-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |