SCHEMBL31679013

SCHEMBL31679013

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC12CCC(CC1)CC2)C(=O)N[C@@H](CCCCNC(=O)OCc1ccccc1)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 9/20 0.48
▸ CTSL P07711 1/20 0.47
▸ NPY1R P25929 6/20 0.46
▸ NPY2R P49146 4/20 0.46
▸ NPY5R Q15761 4/20 0.46
▸ PTGER4 P35408 4/20 0.43
▸ SIRT2 Q8IXJ6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31679017 0.93 CTSL (0.49) NPY4RCTSLNPY1RNPY2RNPY5R
SCHEMBL22117553 0.91 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL22117551 0.91 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL22117490 0.90 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL22117440 0.90 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL22117439 0.90 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5R
SCHEMBL31679030 0.89 KLK7 (0.49) NPY4RCTSLNPY1RNPY2RNPY5R
SCHEMBL31679028 0.88 DPP8 (0.49) CTSLSIRT2
SCHEMBL22117499 0.87 SIRT2 (0.49) CTSLPTGER4SIRT2
SCHEMBL22117498 0.87 SIRT2 (0.49) CTSLPTGER4SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404300-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2025-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404300-B2 Mitochondria-targeting peptides SSBP1, HSPE1, IMMT NPY4R 2540/4885CTSL 1491/4885NPY1R 2382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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