Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.69 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.69 |
| ▸ | HTR7 | P34969 | 6/20 | 0.60 |
| ▸ | HTR2C | P28335 | 6/20 | 0.60 |
| ▸ | HTR2B | P41595 | 5/20 | 0.60 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | HTR1D | P28221 | 3/20 | 0.60 |
| ▸ | DRD1 | P21728 | 3/20 | 0.60 |
| ▸ | HRH1 | P35367 | 3/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 2/20 | 0.60 |
| ▸ | HRH2 | P25021 | 2/20 | 0.60 |
| ▸ | HTR1B | P28222 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | HTR5A | P47898 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | DRD5 | P21918 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118444 | 0.92 | HTR2A (0.63) | HTR2AGRM2HTR7HTR2CHTR2B | |
| SCHEMBL22118461 | 0.91 | HTR2A (0.83) | HTR2AGRM2HTR7HTR2CHTR2B | |
| SCHEMBL4078621 | 0.82 | HTR2A (1.00) | HTR2AGRM2HTR7HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4072830 | 0.81 | HTR2A (0.98) | HTR2AGRM2HTR7HTR2CHTR2B | |
| Volinanserin SCHEMBL22118462 | 0.78 | HTR2B (0.69) | HTR2AHTR7HTR2CHTR2BHTR1D | |
| SCHEMBL5968621 | 0.75 | HTR2A (1.00) | HTR2AGRM2HTR7HTR2CHTR2B | |
| SCHEMBL5968525 | 0.74 | HTR2A (0.79) | HTR2AGRM2HTR7HTR2CHTR2B | |
| SCHEMBL13701274 | 0.73 | HTR2A (0.84) | HTR2AGRM2HTR7HTR2CHTR2B | |
| SCHEMBL13701275 | 0.73 | HTR2A (0.71) | HTR2AGRM2HTR7HTR2CHTR2B | |
| SCHEMBL22118493 | 0.73 | HTR2A (0.44) | HTR2AGRM2HTR7HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066302-A1 | DEUTERATED FORMS AND DERIVATIVES OF VOLINANSERIN | TERRAN BIOSCIENCES INC. | 2025-02-27 | — | — | US | disclosed |
| US-20220106272-A1 | Deuterated Forms And Derivatives Of Volinanserin | TERRAN BIOSCIENCES, INC. | 2022-04-07 | — | — | US | disclosed |
| EP-3897507-A1 | DEUTERATED FORMS AND DERIVATIVES OF VOLINANSERIN | Concert Pharmaceuticals Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132461-A1 | DEUTERATED FORMS AND DERIVATIVES OF VOLINANSERIN | CONCERT PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066302-A1 | DEUTERATED FORMS AND DERIVATIVES OF VOLINANSERIN | DRD2, HTR3A, COMT | HTR2A 16/4885GRM2 848/4885HTR7 21/4885 |
| US-20220106272-A1 | Deuterated Forms And Derivatives Of Volinanserin | DRD2, HTR3A, COMT | HTR2A 16/4885GRM2 848/4885HTR7 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.