Styrene

Styrene

SCHEMBL22119548

C=Cc1ccccc1.c1cnnnn1

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
TSHR P16473 1/20 0.67
TDP1 Q9NUW8 2/20 0.37
TP53 P04637 1/20 0.37
CYP11B2 P19099 3/20 0.35
CYP11B1 P15538 1/20 0.35
MAOB P27338 2/20 0.35
CYP2A6 P11509 1/20 0.35
HDAC8 Q9BY41 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
POLB P06746 1/20 0.32
CYP19A1 P11511 2/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 2/20 0.31
ADRA2A P08913 1/20 0.31
MAOA P21397 1/20 0.31
NISCH Q9Y2I1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1726001 0.91 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53CYP11B2
Styrene SCHEMBL7045807 0.91 ALDH1A1 (0.67) ALDH1A1TSHRTDP1TP53CYP11B2
Styrene SCHEMBL9279039 0.88 ALDH1A1 (0.52) ALDH1A1TSHRTDP1TP53HDAC8
Styrene SCHEMBL8338093 0.84 ALDH1A1 (0.93) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL1170787 0.84
Styrene SCHEMBL30763628 0.82 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53MAOB
Styrene SCHEMBL28366334 0.82 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53CYP11B2
Styrene SCHEMBL27670659 0.82 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53CYP11B2
Styrene SCHEMBL6745975 0.82 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53CYP11B2
Styrene SCHEMBL5344586 0.82 ALDH1A1 (0.88) ALDH1A1TSHRTDP1TP53CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347572-A1 AMINO ACIDS BEARING A TETRAZINE MOIETY VALANX Biotech GmbH (AT) 2024-04-10 EP disclosed
CN-117730076-A Amino acids containing tetrazine moieties 瓦朗斯生物技术有限公司 2024-03-19 CN disclosed
WO-2020132301-A1 VARIABLE LYMPHOCYTE RECEPTORS THAT TARGET THE BRAIN EXTRACELLULAR MATRIX AND METHODS OF USE WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2020-06-25 WO disclosed