Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 20/20 | 0.42 |
| ▸ | DRD3 | P35462 | 8/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2209598 | 0.87 | ADRB2 (0.43) | ADRB2ADRB1DRD3 | |
| SCHEMBL2214145 | 0.86 | ADRB2 (0.42) | ADRB2ADRB1DRD3 | |
| SCHEMBL2213175 | 0.83 | ADRB2 (0.58) | ADRB2ADRB1DRD3 | |
| SCHEMBL2814220 | 0.82 | ADRB2 (0.40) | ADRB2ADRB1DRD3 | |
| SCHEMBL2213782 | 0.80 | ADRB2 (0.38) | ADRB2ADRB1DRD3 | |
| SCHEMBL2211368 | 0.80 | ADRB2 (0.38) | ADRB2ADRB1DRD3 | |
| SCHEMBL2213787 | 0.79 | ADRB2 (0.39) | ADRB2ADRB1DRD3 | |
| SCHEMBL2212002 | 0.79 | ADRB2 (0.43) | ADRB2ADRB1DRD3 | |
| SCHEMBL2210752 | 0.78 | ADRB2 (0.40) | ADRB2ADRB1DRD3 | |
| SCHEMBL2211946 | 0.74 | ADRB2 (0.45) | ADRB2ADRB1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121642-B1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2011-07-27 | — | — | EP | disclosed |