Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214145 | 0.93 | ADRB2 (0.42) | ADRB2ADRB1DRD3 | |
| SCHEMBL2209598 | 0.93 | ADRB2 (0.43) | ADRB2ADRB1DRD3 | |
| SCHEMBL2211368 | 0.90 | ADRB2 (0.38) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL2213782 | 0.90 | ADRB2 (0.38) | ADRB2ADRB1DRD3DRD2 | |
| SCHEMBL2210752 | 0.90 | ADRB2 (0.40) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL2211946 | 0.82 | ADRB2 (0.45) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL2815992 | 0.81 | ADRB2 (0.39) | ADRB2ADRB1 | |
| SCHEMBL2213432 | 0.80 | ADRB2 (0.41) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL2212530 | 0.80 | ADRB2 (0.43) | ADRB2ADRB1DRD3DRD2ADRA1D | |
| SCHEMBL2212004 | 0.79 | ADRB2 (0.42) | ADRB2ADRB1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121642-B1 | 4-HYDR0XY-2-0X0-2, 3 -DIHYDRO- 1, 3-BENZOTHIAZOL- 7YL COMPOUNDS FOR MODULATION OF B2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2011-07-27 | — | — | EP | disclosed |