Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22162895 | 1.00 | PYCR1 (0.42) | PYCR1PPARAALOX15ALOX12PPARG | |
| SCHEMBL22145306 | 0.84 | PYCR1 (0.40) | PYCR1PPARAALOX15ALOX12PPARG | |
| SCHEMBL22122785 | 0.82 | PYCR1 (0.44) | PYCR1PPARAALOX15ALOX12PPARG | |
| SCHEMBL30485975 | 0.82 | PYCR1 (0.44) | PYCR1PPARAALOX15ALOX12PPARG | |
| SCHEMBL22145313 | 0.82 | PYCR1 (0.44) | PYCR1PPARAALOX15ALOX12PPARG | |
| SCHEMBL3237063 | 0.82 | IDO1 (0.47) | ALOX15ALOX12MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22125042 | 0.82 | PYCR1 (0.46) | PYCR1PPARAALOX15ALOX12PPARG | |
| SCHEMBL22122732 | 0.81 | ALOX15 (0.46) | PYCR1PPARAALOX15ALOX12PPARG | |
| SCHEMBL22124303 | 0.80 | PYCR1 (0.40) | PYCR1PPARAALOX15ALOX12PPARG | |
| SCHEMBL22162357 | 0.80 | PYCR1 (0.40) | PYCR1PPARAALOX15ALOX12PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898633-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020127504-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |